Results 201 to 210 of about 375,773 (265)
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Epigenetic processes in sporadic parathyroid neoplasms
Molecular and Cellular Endocrinology, 2017Parathyroid tumors (PTs) are highly variable in their genetic background. Increasing evidence demonstrates that endocrine diseases can be caused by epigenetic alterations. The present review is focused on epigenetic aberrations related to PTs. DNA methylation, posttranslational histone modification, and noncoding RNAs are epigenetic mechanisms involved
Angelica M. Silva-Figueroa, N. Perrier
semanticscholar +4 more sources
Parathyroid Neuroendocrine Neoplasms
, 2020The parathyroid glands are the site of common benign neuroendocrine tumors, including adenomas and lipoadenomas. Metastatic disease is very rare, and local growth does not usually have significant sequelae; even large non-metastatic tumors are easily resected.
S. Asa, O. Mete
semanticscholar +3 more sources
EZH2 and ZFX oncogenes in malignant behaviour of parathyroid neoplasms
Endocrine, 2016Several studies reported somatic mutations of many genes (MEN1, CTNNB1, CDKIs and others) in parathyroid adenoma, although with different prevalence. Recently, activating mutations of the EZH2 and ZFX oncogenes were identified in benign parathyroid adenoma by whole exome sequencing. The same mutations had been found in blood and ovary malignant tumours.
E. Sanpaolo +11 more
semanticscholar +4 more sources
Endocrine Pathology, 2019
Parathyroid adenomas are slow growing benign neoplasms associated with hypercalcemia, while atypical parathyroid adenomas and parathyroid carcinomas are uncommon tumors and their histologic features may overlap with parathyroid adenomas. LncRNAs participate in transcription and in epigenetic or post-transcriptional regulation of gene expression, and ...
Qiqi Yu +4 more
semanticscholar +4 more sources
Parathyroid adenomas are slow growing benign neoplasms associated with hypercalcemia, while atypical parathyroid adenomas and parathyroid carcinomas are uncommon tumors and their histologic features may overlap with parathyroid adenomas. LncRNAs participate in transcription and in epigenetic or post-transcriptional regulation of gene expression, and ...
Qiqi Yu +4 more
semanticscholar +4 more sources
[Diagnosis and surgical treatment of parathyroid neoplasms].
Zhonghua yi xue za zhi, 2013OBJECTIVE To explore the clinical features, diagnosis and surgical treatment of parathyroid neoplasms. METHODS From January 2003 to December 2011, a total of 51 patients were recruited.
Shanting Liu +7 more
semanticscholar +4 more sources
Thyroid and Parathyroid Neoplasms
, 2011This chapter offers an overview of the epidemiology and aetiology, clinical and histological characteristics and classification, and staging of thyroid and parathyroid neoplasms before providing a more focused and illustrated description of the imaging findings. The indications and the role of ultrasound, ultrasound-guided fine needle aspiration, cross-
P. Richards
semanticscholar +3 more sources
Salivary Gland, Thyroid, and Parathyroid Neoplasms: Molecular Features [PDF]
, 2018 Tumors involving the salivary, thyroid, and parathyroid glands in the pediatric age group range from benign tumors, to indeterminant malignant potential tumors to frankly malignant tumors. In addition, certain tumors may be associated with hereditary syndromes.
M. Hicks
semanticscholar +2 more sources
Fine needle cytology pre‐surgical differentiation of parathyroid neoplasms: Is it reliable?
Cytopathology, 2017Fine needle cytology (FNC) of a parathyroid neoplasia (PN) is reliable, but needs to be confirmed by Parathormone (PTH) and Thyroglobulin (TG) immunoassay on needle washing or by immunocytochemistry (ICC) evaluation.
A. Caleo +9 more
semanticscholar +5 more sources
Analysis of Parathyroid Neoplasms by Interphase Fluorescence In Situ Hybridization
The American Journal of Surgical Pathology, 2004Recent studies have indicated that numerical chromosomal abnormalities, including changes in cyclin D1 and p53, may be involved in parathyroid tumorigenesis.
L. Erickson +5 more
semanticscholar +4 more sources
Parathyroid neoplasms: clinical, histopathological, and tissue microarray-based molecular analysis.
Human Pathology, 2003We studied 45 patients with typical and 8 with atypical parathyroid adenomas as well as 20 with parathyroid carcinomas. Clinical, pathological, and molecular analyses were conducted on all adenomas.
A. Stojadinovic +8 more
semanticscholar +3 more sources