Results 211 to 220 of about 25,658 (267)

Spectrum of mitochondrial genomic variation in parathyroid neoplasms

Endocrine, 2021
Mitochondrial DNA (mtDNA) variations have been implicated in various cancer types. Several attempts have been made in benign parathyroid adenoma (PA); however, mtDNA variants and copy number alterations have not been investigated in parathyroid carcinoma (PC).
Ya Hu   +7 more
openaire   +2 more sources

Parathyroid Neuroendocrine Neoplasms

2020
The parathyroid glands are the site of common benign neuroendocrine tumors, including adenomas and lipoadenomas. Metastatic disease is very rare, and local growth does not usually have significant sequelae; even large non-metastatic tumors are easily resected.
Sylvia L. Asa   +4 more
openaire   +2 more sources

Differentiating Atypical Parathyroid Neoplasm from Parathyroid Cancer

Annals of Surgical Oncology, 2016
The differentiation of benign parathyroid gland atypia and true parathyroid carcinoma (PC) can be challenging. In some instances, patients are classified as having 'atypical parathyroid neoplasms' (APNs), explicitly acknowledging that the distinction between benign and malignant disease appears impossible to determine.
Michelle D. Williams   +9 more
openaire   +3 more sources

[Clinical analysis of parathyroid neoplasms].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2010
目的 探讨甲状旁腺良性肿瘤的诊断及治疗经验.方法 回顾性分析6例甲状旁腺良性肿瘤患者的临床资料,其中女2例,男4例;年龄为36~62岁,中位年龄59岁.结果 6例甲状旁腺良性肿瘤中甲状旁腺腺瘤5例,甲状旁腺囊肿1例,4例伴有甲状旁腺功能亢进症状,6例患者血钙、血磷血甲状旁腺激素均升高.术前多普勒超声定位的诊断准确率为66.7%(4/6),甲状旁腺显像定位诊断准确率为60%(3/5).6例患者均行肿瘤切除和(或)探查术,均获得临床治愈.随访时间5个月至3年,中位随访时间2年.结论 临床医师应对高度怀疑甲状旁腺疾病的患者进行血钙、血磷、血甲状旁腺激素检测.术前影像学检查应首选多普勒超声,并辅以甲状旁腺显像检查.手术切除是最佳的治疗手段.
Xiu-mei Chen, Qing-quan Zhang
openaire   +3 more sources

Epigenetic processes in sporadic parathyroid neoplasms

Molecular and Cellular Endocrinology, 2018
Parathyroid tumors (PTs) are highly variable in their genetic background. Increasing evidence demonstrates that endocrine diseases can be caused by epigenetic alterations. The present review is focused on epigenetic aberrations related to PTs. DNA methylation, posttranslational histone modification, and noncoding RNAs are epigenetic mechanisms involved
Angelica M. Silva-Figueroa   +1 more
openaire   +3 more sources

[Diagnosis and surgical treatment of parathyroid neoplasms].

Zhonghua yi xue za zhi, 2013
To explore the clinical features, diagnosis and surgical treatment of parathyroid neoplasms.From January 2003 to December 2011, a total of 51 patients were recruited. Their clinical data, presentations, examinations and surgical approaches were analyzed retrospectively.Among them, there were parathyroid adenoma (n = 32), parathyroid cysts (n = 18) and ...
Qi Jx   +7 more
openaire   +3 more sources

Thyroid and Parathyroid Neoplasms

2020
The thyroid and adjacent parathyroid glands demonstrate a variety of benign and malignant pathology, with nodular thyroid disease being the most common pathology encountered in most routine head and neck imaging practice. A variety of thyroid cancers exist, and imaging strategy for staging, surveillance and follow-up depend upon the cancer type.
openaire   +2 more sources

EZH2 and ZFX oncogenes in malignant behaviour of parathyroid neoplasms

Endocrine, 2016
Several studies reported somatic mutations of many genes (MEN1, CTNNB1, CDKIs and others) in parathyroid adenoma, although with different prevalence. Recently, activating mutations of the EZH2 and ZFX oncogenes were identified in benign parathyroid adenoma by whole exome sequencing. The same mutations had been found in blood and ovary malignant tumours.
E. Sanpaolo   +11 more
openaire   +3 more sources

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