Novel mutations in the toll like receptor genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection [PDF]
, 2008 Toll like receptors play a central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in TLR1, TLR2 and TLR4 genes may change the PAMP reorganization ability which causes altered responsiveness to the bacterial pathogens.
Ivan Mikula Jr. +6 more
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Clinical Microbiology Reviews, 1994 Paratuberculosis (Johne's disease) is a chronic, wasting, widespread mycobacteriosis of ruminants. It involves extensive mycobacterial shedding, which accounts for the high contagiousness, and ends with a fatal enteritis. Decreases in weight, milk production, and fertility produce severe economic loss.
Cocito, C +5 more
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Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains [PDF]
, 2013 BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks
Bull, TJ +7 more
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Protection efficacy of Argentinian isolates of Mycobacterium avium subsp. paratuberculosis with different genotypes and virulence in a murine model [PDF]
, 2018 Paratuberculosis is a chronic disease caused by Mycobacterium avium subsp. paratuberculosis (Map). The disease causes economic losses and, therefore, it is imperative to follow proper control strategies, which should include an effective vaccine. Several
Alvarado Pinedo, María Fiorella +8 more
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Diagnosis and Treatment of Infectious Enteritis in Adult Ruminants. [PDF]
, 2018 Infectious enteritis in adult ruminants is often a result of 1 or more viral, bacterial, or parasitic pathogens. Diagnosis of etiologic agents causing enteritis is important when considering herd implications and zoonotic potential of some etiologies ...
Chigerwe, Munashe, Heller, Meera C
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Vaccination against paratuberculosis
Expert Review of Vaccines, 2008 Johne's disease, or paratuberculosis, is a chronic granulomatous enteritis in ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP) affecting principally cattle, sheep and goats. Primarily, there are two clinical signs: cachexia and chronic diarrhea (less common in goats and sheep).
Valérie, Rosseels, Kris, Huygen
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Zinc transporter 8 and MAP3865c homologous epitopes are recognized at T1D onset in Sardinian children [PDF]
, 2013 Our group has recently demonstrated that Mycobacterium avium subspecies paratuberculosis (MAP) infection significantly associates with T1D in Sardinian adult patients.
Carlo Ripoli +5 more
core +3 more sources
Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]
, 2006 The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Fischer, Simon +4 more
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In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]
, 2008 Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD +3 more
core +1 more source
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 1960 Yurdumuz ekonomisinde bilhassa sığırların önemi göz önünde tutularak gerek haralarımız ve inekhanelerimiz, gerekse halk tarafından yapılan intensiv sığır yetiştiriciliğinde Paratüberküloz enfeksiyonu hakkında yetiştirme şube lerine, kliniklere ve mücadele işlerine yeni intisap etmiş genç meslektaşları mıza geniş bir bilgi vermeyi faydalı bulduk.
openaire +3 more sources