Results 1 to 10 of about 186,333,048 (184)
Role of the Paraventricular Nucleus of the Hypothalamus in Sleep–Wake Regulation
Brain Science Advances, 2022 The paraventricular nucleus of the hypothalamus (PVH) acts as a cohesive functional unit that regulates neuroendocrine and autonomic function, complex behavior, and negative emotions after stress.
Zhi-Li Huang, Chang-Rui Chen
exaly +2 more sources
Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus
eLife, 2020 The nucleus of the solitary tract (NTS) is critical for the central integration of signals from visceral organs and contains preproglucagon (PPG) neurons, which express leptin receptors in the mouse and send direct projections to the paraventricular ...
Jessica E Biddinger +3 more
doaj +3 more sources
Spatial Transcriptomics of Supraoptic Nucleus and Paraventricular Nucleus of the Hypothalamus
The FASEB Journal, 2021 Magnocellular neurosecretory cells (MNCs) in the supraoptic nucleus (SON) and paraventricular nucleus (PVN) of the hypothalamus release oxytocin (OXY) and arginine vasopressin (AVP) into the peripheral circulation, playing a key role in the regulation of fluid and electrolyte homeostasis.
Dianna Nguyen +2 more
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The Paraventricular Nucleus of the Hypothalamus: Development, Function, and Human Diseases [PDF]
Endocrinology, 2018 The paraventricular nucleus of the hypothalamus (PVH), located in the ventral diencephalon adjacent to the third ventricle, is a highly conserved brain region present in species from zebrafish to humans. The PVH is composed of three main types of neurons, magnocellular, parvocellular, and long-projecting neurons, which play imperative roles in the ...
Cheng, Qin, Jiaheng, Li, Ke, Tang
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Paraventricular Nucleus of the Hypothalamus Oxytocin and Incubation of Heroin Seeking
Neuroendocrinology, 2023 <b><i>Introduction:</i></b> There are numerous pharmacologic treatments for opioid use disorder (OUD), but none that directly target the underlying addictive effects of opioids. Oxytocin, a peptide hormone produced in the paraventricular nucleus (PVN) of the hypothalamus, has been investigated as a potential therapeutic for OUD.
Carter, Jordan S. +4 more
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Ghrelin indirectly activates hypophysiotropic CRF neurons in rodents. [PDF]
PLoS ONE, 2012 Ghrelin is a stomach-derived hormone that regulates food intake and neuroendocrine function by acting on its receptor, GHSR (Growth Hormone Secretagogue Receptor). Recent evidence indicates that a key function of ghrelin is to signal stress to the brain.
Agustina Cabral +3 more
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Simulated high altitude hypoxia induces anxiety- and depression-like behaviors in mice
Di-san junyi daxue xuebao, 2021 Objective To determine the effects of simulated altitude hypoxia conditions on anxiety- and depression-like behaviors in mice. Methods C57 adult male mice were divided into 3 groups (n=10): plain control group, 24 h plateau hypoxia group, and 7 d plateau
ZHAO Jinghui +7 more
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Nature Communications, 2020 The TrkB receptor is known to regulate obesity via appetite control, but the underlying neural circuits are not known. Here, the authors show that selective modulation of TrkB+ neurons in the paraventricular hypothalamus regulates food intake via ...
Juan Ji An +5 more
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Role of the Paraventricular Nucleus of the Hypothalamus in the Sympathoexcitatory Effects of Leptin [PDF]
Hypertension, 2015 Leptin binds to receptors in multiple hypothalamic nuclei to increase sympathetic nerve activity; however, the neurocircuitry is unclear. Here, using anesthetized male Sprague–Dawley rats, we investigated the role of the paraventricular nucleus of the hypothalamus.
Zhigang, Shi +2 more
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Frontiers in Neuroscience, 2015 Sexual behavior is suppressed by various types of stressors. We previously demonstrated that an alarm pheromone released by stressed male Wistar rats is a stressor to other rats, increases the number of mounts needed for ejaculation, and decreases the ...
Tatsuya eKobayashi +3 more
doaj +1 more source