Results 61 to 70 of about 186,333,048 (184)

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Acupuncture Alleviates Allergic Rhinitis by Activating the AMPK/PGC‐1α Pathway to Attenuate Mitochondrial Oxidative Stress and Restore Epithelial Barrier Function

open access: yesFlavour and Fragrance Journal, EarlyView.
Acupuncture at Feishu (BL13), Shenshu (BL23), Yingxiang (LI20), and Dazhui (GV14) alleviates allergic rhinitis by activating the AMPK/PGC‐1α/NRF1/TFAM signalling axis. This activation improves mitochondrial biogenesis and function, reduces mtROS‐mediated oxidative stress, restores ATP production and respiratory complex I/IV activity, suppresses IgE and
Fengying Zhang   +3 more
wiley   +1 more source

Presença de receptores serotonérgicos no núcleo paraventricular do hipotálamo e sua participação no controle neural da ingestão de alimentos em pombos (Columba livia) [PDF]

open access: yes, 2001
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Mestrado em NeurociênciasInvestigação do possível envolvimento de receptores serotonérgicos presentes no Núcleo Paraventricular do Hipotálamo na regulação de ...
Silva, Aderley Serenita Sartori da
core  

Repeated Stress Impairs Endocannabinoid Signaling in the Paraventricular Nucleus of the Hypothalamus [PDF]

open access: yesThe Journal of Neuroscience, 2010
Endocannabinoids (eCBs) are ubiquitous retrograde signaling molecules in the nervous system that are recruited in response to robust neuronal activity or the activation of postsynaptic G-protein-coupled receptors. Physiologically, eCBs have been implicated as important mediators of the stress axis and they may contribute to the rapid feedback ...
Jaclyn I, Wamsteeker   +2 more
openaire   +2 more sources

Extraocular Photoreception in Optic Lobes, Suckers, and Skin of Octopus vulgaris

open access: yesIntegrative Zoology, EarlyView.
Evidence of extra‐ocular photoreception in Octopus vulgaris (a) Diagram of the O. vulgaris different tissues considered: SPB, sucker proximal big; SPL, sucker proximal large; SM, sucker medium; SD, sucker distal; SK, skin; OL, optic lobes; RT, retina; (b‐d) Gene expression analysis of Ov‐GRK1 (red), Ov‐retinochrome (green), Ov‐rhodopsin (blue) mRNA ...
Valeria Maselli   +7 more
wiley   +1 more source

Whole-Brain Monosynaptic Afferent Projections to the Cholecystokinin Neurons of the Suprachiasmatic Nucleus

open access: yesFrontiers in Neuroscience, 2018
The suprachiasmatic nucleus (SCN) is the principal pacemaker driving the circadian rhythms of physiological behaviors. The SCN consists of distinct neurons expressing neuropeptides, including arginine vasopressin (AVP), vasoactive intestinal polypeptide (
Xiang-Shan Yuan   +6 more
doaj   +1 more source

Hypertension in Prenatally Undernourished Young-Adult Rats Is Maintained by Tonic Reciprocal Paraventricular–Coerulear Excitatory Interactions

open access: yesMolecules, 2021
Prenatally malnourished rats develop hypertension in adulthood, in part through increased α1-adrenoceptor-mediated outflow from the paraventricular nucleus (PVN) to the sympathetic system.
Bernardita Cayupe   +10 more
doaj   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

open access: yesIntegrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Glucose‐dependent insulinotropic polypeptide receptor systems in the hypothalamus and the brainstem regulate feeding and weight through distinct pathways

open access: yesJournal of Diabetes Investigation
The report by Adriaenssens et al. in JCI Insight 22 May 2023 explored the role and property of the neurons that express glucose‐dependent insulinotropic polypeptide receptor (GIPR) in the brainstem and hypothalamus.
Toshihiko Yada
doaj   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

open access: yesBritish Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė   +5 more
wiley   +1 more source

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