Results 111 to 120 of about 268,641 (302)

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren   +5 more
wiley   +1 more source

Parental Stress and Mental Health Outcomes Following the October 7th Events: Insights from Israeli Families of Children with Special Needs

open access: yesBehavioral Sciences
The October 7th events precipitated an unprecedented psychological crisis for Israeli families, particularly affecting parents of children with special needs.
Yitshak Alfasi, Ruth Maytles, Avi Besser
doaj   +1 more source

РОДИТЕЛЬСКАЯ КОМПЕТЕНЦИЯ КАК ФАКТОР СОВРЕМЕННОГО СОДЕРЖАНИЯ ОБРАЗОВАНИЯ

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
Автором статьи выявлены вызовы современного общества, обусловливающие трансформацию института семьи, связанные с социально-экономической ситуацией в обществе.
Tatyana Vladimirovna Kovalenko
doaj   +1 more source

Variation in sport participation, fitness and motor coordination with socioeconomic status among Flemish children [PDF]

open access: yes, 2012
Socioeconomic status (SES) is often indicated as a factor that influences physical activity and associated health outcomes. This study examined the relationship between SES and sport participation, morphology, fitness and motor coordination in a sample ...
Lefevre, Johan   +6 more
core   +2 more sources

A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection

open access: yesAdvanced Science, EarlyView.
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang   +8 more
wiley   +1 more source

Reality is in the eye of the beholder: From young players’ interpretations of their parents to how they perceive their own competence and the value of sport

open access: yesPsychTech & Health Journal
The expectancy-value theory posits that expectations of success and the value placed on a task are critical determinants of motivation and learning.
Filipa Rocha   +2 more
doaj   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

open access: yesAdvanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua   +6 more
wiley   +1 more source

Young children's perspectives of time: New directions for co‐constructing understandings of quality in ECEC

open access: yesBritish Educational Research Journal, EarlyView., 2023
Abstract Children's relationship with time in preschools is an under‐researched area. Young children rarely know how to measure time using a clock, but their experiences of time may contribute to understanding children's well‐being and debates about quality in preschools.
Kristín Dýrfjörð   +3 more
wiley   +1 more source

Children’s Well-Being in Primary School: Pupil and School Effects [Wider Benefits of Learning Research Report No. 25] [PDF]

open access: yes, 2008
This study investigates pupil and school effects on children’s well-being between the ages of 8 and 10. We found that most children experience positive well-being in primary school.
Feinstein, Leon, Gutman, Leslie
core   +1 more source

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