Results 51 to 60 of about 1,093,834 (288)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Parental intelligence and preschoolers' social competence: the mediating role of parental attachment behavior and the moderating effect of parent gender—A multi-informant study

Frontiers in Developmental Psychology
BackgroundDeficits in preschoolers' social competence—encompassing emotional understanding, peer cooperation, and conflict resolution—pose significant risks for later school adjustment and interpersonal relationships.
Xiang Ji, Yujie Zhang, Yu Zuo, Chuanzhen Ji, Yiya Xu, Peilai Jin, Miaomiao Wang   +6 more
doaj   +1 more source

Parental competence programs to promote positive parenting and healthy lifestyles in children: a systematic review.

Jornal de Pediatria, 2017
OBJECTIVE To analyze the available evidence regarding the efficacy of interventions on parents whose children were aged 2-5 years to promote parental competence and skills for children's healthy lifestyles.
Cayetana Ruíz-Zaldibar, Inmaculada Serrano-Monzó, A. Mujika   +2 more
semanticscholar   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

On the Attribution of Parental Competence: Parents’ Behavior Matters, not Their Sexual Orientation

Journal of Child and Family Studies, 2022
AbstractUsing a vignette approach, two studies examined the impact of three factors on judgments of parental competence: target parents’ sexual orientation, gender, and parenting behavior. According to the aversive prejudice framework, people should express their subtle prejudice against lesbian and gay parents when the latter show detrimental ...
openaire   +2 more sources

Parents' management of alcohol in the context of discourses of ‘competent’ parenting: A qualitative analysis

Sociology of Health & Illness, 2022
AbstractHow parents manage potential tensions between normative discourses of ‘competent parenting’ and their desires to consume alcohol has received little attention. In this article, we explore the elements that encourage or constrain parents' drinking and investigate how parents consider and manage their alcohol use in the context of multiple social
Megan Cook, Amy Pennay, Sarah MacLean, Robyn Dwyer, Janette Mugavin, Sarah Callinan   +5 more
openaire   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Self-esteem as a predictor of career decision-making competence in middle school students: The mediating role of parental career-related support

International Journal of Turkish Education Sciences
The purpose of this study is to examine the mediating role of parental career-related support in the relationship between self-esteem and career decision-making competence among middle school students.
Ahmet Toplu, Asude Özdemir
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source