Results 71 to 80 of about 136,527 (299)

Examining the Links Between Challenging Behaviors in Youth with ASD and Parental Stress, Mental Health, and Involvement: Applying an Adaptation of the Family Stress Model to Families of Youth with ASD [PDF]

, 2018
Raising a child with autism spectrum disorder (ASD) poses unique challenges that may impact parents’ mental health and parenting experiences. The current study analyzed self-report data from 77 parents of youth with ASD. A serial multiple mediation model
Caiozzo, Christina, Carson, Audrey Meyer, Dolan, Bridget Kathleen, Karst, Jeffrey S., Magnus, Brooke E., McVey, Alana J., Pleiss, Sheryl, Schiltz, Hillary, Van Hecke, Amy V., Vogt, Elisabeth M., Willar, Kirsten S.   +10 more
core   +1 more source

Computer‐Mediated Support Group Intervention for Parents [PDF]

Journal of Nursing Scholarship, 2008
Purpose : The purpose of this study was to evaluate the feasibility of a computer‐mediated support group (CMSG) intervention for parents whose children had been diagnosed with cancer. Design and Methods : An evaluative one‐group, before‐and‐after research design.
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

How do autistic severity and family functioning influence parental stress in caregivers of children with autism spectrum disorder in China? The important role of parental self-efficacy

Frontiers in Psychology, 2023
IntroductionParental stress among primary caregivers of children with autism spectrum disorder (ASD) is a significant concern. While previous research indicates that both family and child factors substantially influence parental stress, a few studies ...
Tomoko Kishimoto, Shuang Liu, Lumei Zhang, Shaowei Li   +3 more
doaj   +1 more source

Parental readiness, parental care, and adolescent school performance among commuter families in Malaysia: a mediation model [PDF]

, 2014
This study aimed (i) to examine the relationship between parental readiness, parental care, and adolescent school performance; and (ii) to test the role of parental care as mediator between parental readiness to commute and the adolescent school ...
Abdullah, Haslinda, Abdullah, Maria Chong, Roslan, Samsilah, Siaw, Yan Li   +3 more
core  

Mediating social media use: Connecting parents’ mediation strategies and social media literacy [PDF]

Cyberpsychology: Journal of Psychosocial Research on Cyberspace, 2017
Increasingly complex and multipurpose social media platforms require digital competences from parents and adolescents alike. While adolescents grow up with social media, parents have more difficulties with them, leading to uncertainties regarding their adolescents’ social media mediation.
Daneels, Rowan, Vanwynsberghe, Hadewijch
openaire   +4 more sources

Fathers’ parenting stress, parenting styles and children’s problem behavior: the mediating role of parental burnout

Current Psychology, 2022
Abstract Parental duties can be overwhelming, particularly when parents lack sufficient resources to cope with parenting demands, leading to parental burnout. Research has shown that parental burnout is positively related to neglect and abuse behaviors towards their children; however, few studies have examined parental burnout within the family system,
Yifan Ping, Wei Wang, Yimin Li, Yongxin Li   +3 more
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Parental mediation and adolescent internet addiction: The role of parent-child relationship and parental internet addiction

Acta Psychologica
Prior research has consistently shown a negative association between parental mediation and adolescent internet addiction. However, this study provides new evidence suggesting that the relationship between the two may be more complex, exhibiting both ...
Sikang Zhang, Zengquan Fang, Xuejing Qi, Ying Yuan   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source