Results 71 to 80 of about 585,089 (288)

Risk of selection bias due to non-participation in a cohort study on pubertal timing. [PDF]

, 2020
BackgroundNon-participation in aetiologic studies of pubertal timing is frequent. However, little effort has been given to explore the risk and potential impact of selection bias in studies of pubertal timing.ObjectiveWe aimed to explore the risk of ...
Arah, Onyebuchi A, Brix, Nis, Ernst, Andreas, Henriksen, Tine Brink, Lauridsen, Lea Lykke Braskhøj, Olsen, Jørn, Parner, Erik Thorlund, Ramlau-Hansen, Cecilia Høst   +7 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Parental educational level in shaping student participation in lesson activities: A multifaceted study [PDF]

OUSL Journal
This research study delves into the complex relationship between parental educational background and student participation in lesson activities in the context of secondary school education in Sri Lanka.
Jalal Deen Careemdeen
doaj   +1 more source

The Determinants of Higher Education Participation in Ireland: A Micro Analysis [PDF]

In this paper we present a theoretical model of higher education participation in Ireland. Utilising the Living in Ireland Survey data we model the impact of costs (direct and indirect), the estimated life cycle returns, environmental and parental ...
Flannery, Darragh, O'Donoghue, Cathal
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Labour Market Effects of Parental Leave: A European Perspective [PDF]

We investigate the aggregate-level effects of parental leave legislation on various labour market outcomes of women in 16 European countries for the period since 1970. The paper updates and extends previous findings in the literature.
Janneke Plantenga, Yusuf Emre Akgunduz
core  

Out-of-school lives of physically disabled children and young people in the United Kingdom: A qualitative literature review [PDF]

, 2014
Currently there appears to be few opportunities and little evidence of physically disabled children and young people (C&YP) participating in mainstream social activities.
Beresford B, Department of Health, Department of Health (DOH), Department of Work and Pensions, Langer S, National Institute for Health and Clinical Excellence (NICE), The Bevan Foundation   +6 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Are the correlates of sport participation similar to those of screen time?

Preventive Medicine Reports, 2015
Objective: To explore longitudinal and cross-sectional correlates of sport participation and screen time in a nationally representative sample of Australian children.
Mark S. Allen, Stewart A. Vella
doaj   +1 more source