Results 81 to 90 of about 585,089 (288)
Fathers' childcare and parental leave policies: Evidence from Western European Countries and Canada [PDF]
The study at hand pursues the following question: How are national parental leave arrangements related to fathers' participation in and time used for childcare?
Boll, Christina +2 more
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
, 1998 Altogether 2011 local school councils were approached in the GO, 520 participation councils in the VGO, and 219 participation councils in the OGO, divided proportionately over primary and secondary education. The response of'parents' representatives to the questionnaires that were sent wasfairly large.
Van Heddegem, Ilse, Verhoeven, Jef
openaire +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Family support and ease of access link socio-economic status and sports club membership in adolescent girls : a mediation study [PDF]
, 2013 Background Much research has been conducted into the determinants of physical activity (PA) participation among adolescent girls. However, the more specific question of what are the determinants of particular forms of PA participation, such as the link ...
Craike, Melinda J. +4 more
core +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Journal of Sport and Health Science, 2017 Purpose: The objective of this study was to examine the associations between parental support for physical activity (PA) and levels of moderate-to-vigorous physical activity (MVPA) among Chinese school children.
Yang Liu +5 more
doaj +1 more source
Parental Income and the Choice of Participation in University, Polytechnic or Employment at Age Eighteen: A Longitudinal Study [PDF]
This paper examines the link between parental income during adolescent years and higher education choices of the offspring at age 18. This study is the first to use a recent longitudinal data set from New Zealand (Christchurch Health and Development ...
Sholeh A. Maani
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Organized Sports, Overweight, and Physical Fitness in Primary School Children in Germany
Journal of Obesity, 2013 Physical inactivity is associated with poor physical fitness and increased body weight. This study examined the relationship between participation in organized sports and overweight as well as physical fitness in primary school children in southern ...
Clemens Drenowatz +5 more
doaj +1 more source