Results 81 to 90 of about 1,635,829 (363)

Arithmetic in the developing brain: A review of brain imaging studies

Developmental Cognitive Neuroscience, 2018
Brain imaging studies on academic achievement offer an exciting window on experience-dependent cortical plasticity, as they allow us to understand how developing brains change when children acquire culturally transmitted skills. This contribution focuses
Lien Peters, Bert De Smedt
doaj   +1 more source

Multivariate Behavioral Genetic Analysis of Parenting in Early Childhood

, 2016
SYNOPSIS: Objective. Caregivers play an important role in child development; in addition to instilling their norms and values in their children through socialization, caregivers modify their parenting practices in response to children’s characteristics ...
Cheung, Amanda K., Harden, K. Paige, Tucker-Drob, Elliot M.   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Distant mothering, grandparenting, intergenerational coparenting relationship, and child adjustment: evidence from Chinese families with young left-behind children

Frontiers in Psychology
IntroductionIn China, it is a common practice for rural-to-urban migrant parents, due to working conditions, to leave their children with grandparents in their rural hometowns, and to raise their child from a distance (e.g., via mobile phone).
Ruwen Liang, Ruwen Liang, Karla Van Leeuwen   +2 more
doaj   +1 more source

Domestically violent fathers impact children’s social-emotional development: fathers’ psychological functioning, parenting, and co-parenting

, 2020
In the current study we were interested in exploring whether fathers’ depression, parenting over-reactivity and hostility, parenting laxness, parenting rejection, and co-parenting might mediate the relationship between child exposure to domestic violence
Katreeena Scott (8475876)
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A case study for intergenerational transference of parenting in genadendal: Developing guidelines [PDF]

, 2014
Philosophiae Doctor - PhDParenting practices are known to influence the development of children and family functioning. However, the extent to which these generational influences stretch, and the continuities brought forth between generations has not ...
Human-Hendricks, Anja
core   +1 more source

The clinical effectiveness of different parenting programmes for children with conduct problems : a systematic review of randomised controlled trials [PDF]

, 2009
Background Conduct problems are common, disabling and costly. The prognosis for children with conduct problems is poor, with outcomes in adulthood including criminal behaviour, alcoholism, drug abuse, domestic violence, child abuse and a range of ...
Barlow Jane, Bayliss, S, Frew, Emma, Hyde Chris, Stewart-Brown Sarah, Stewart-Brown, Sarah, Sandercock Josie, Frew Emma, Davenport Clare, Taylor, Rod, Stewart-Brown, Sarah L., Davenport, Clare; id_orcid, Taylor, RS, Barlow, Jane, Taylor, Rod S., Bayliss Sue, Dretzke, Janine, Hyde, Christopher, Barlow, J, Davenport, Clare, Sandercock, Josie, Dretzke Janine, Bayliss, Sue, Stewart-Brown, S, Hyde, C, Hyde, Chris, Frew, Emma; id_orcid, Taylor Rod S   +27 more
core   +1 more source

Parenting Stress, Mental Health, Dyadic Adjustment: A Structural Equation Model

Frontiers in Psychology, 2017
Objective: In the 1st year of the post-partum period, parenting stress, mental health, and dyadic adjustment are important for the wellbeing of both parents and the child.
L. Rollé, L. E. Prino, C. Sechi, L. Vismara, E. Neri, C. Polizzi, Annamaria Trovato, B. Volpi, S. Molgora, Valentina Fenaroli, E. Ierardi, V. Ferro, L. Lucarelli, F. Agostini, R. Tambelli, E. Saita, Cristina Riva Crugnola, P. Brustia   +17 more
semanticscholar   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source