Results 91 to 100 of about 260,143 (289)
Child Externalising and Internalising Behaviour in the First Year of School: The Role of Parenting in a Low SES Population [PDF]
Successful transition and adjustment to school life is critical for a child's future success. To ease this transition a child needs to arrive equipped with the necessary skills for school.
Carly Cheevers +2 more
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Family stressors and children's outcomes [PDF]
, 2012 The research reported here aimed to identify:1.which family stress factors and parental behaviours were associated with worse outcomes for children at age 7 andwhich factors helped children to succeed2.whether stressful life events experienced at ...
Gutman, Leslie +2 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Frontiers in PsychologyThe aim of this study was to investigate the associations between parenting styles, young children’s social problem-solving skills, and the mediating role of self-concept in a sample of 200 Turkish preschoolers aged 48–72 months, with an equal ...
Ahmet Ayık +2 more
doaj +1 more source
Parenting behaviours and children's development from infancy to early childhood: Changes, continuities, and contributions [Wider Benefits of Learning Research Report No. 22] [PDF]
, 2007 This study investigated how children and parenting behaviours change from infancy to early childhood, how parenting influences concurrent and future child development, and whether parenting itself is affected by and responsive to child development.
Feinstein, Leon, Gutman, Leslie
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Differential Contributions of Three Parenting Dimensions to Preschool Literacy and Social Skills in a Middle-Income Sample [PDF]
, 2012 This study investigated parenting practices among families of preschoolers in a middle-income community, as well as the contributions of these practices to children\u27s literacy and learning-related social skills. A total of 229 families of preschoolers
Hindman, Annemarie H. +1 more
core +2 more sources
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
The American Family in Black and White: A Post-Racial Strategy for Improving Skills to Promote Equality [PDF]
In contemporary America, racial gaps in achievement are primarily due to gaps in skills. Skill gaps emerge early before children enter school. Families are major producers of those skills.
Heckman, James J.
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