Results 81 to 90 of about 45,473 (256)

Responsive Parenting and Friendship Quality in Adolescents: Interpersonal Communication Skills as a Mediator

Bulletin of Counseling and Psychotherapy
Existing knowledge indicates that responsive parenting significantly influences the quality of friendships among adolescents. However, previous research has not fully elucidated the dynamics within the relationship between responsive parenting and ...
Aaliya Hana Mahirah, Marselius Sampe Tondok   +1 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Development of a Causal Model of Social, Academic, and Emotional Risk-Taking based on Parenting Styles, Sensation-Seeking, Stress Coping Styles Mediated by Academic Skills in Students with High-Risk Behaviors

تحقیقات نظام سلامت, 2021
Background: The aim of this study was to develop a causal model of social, academic, and emotional risk-taking based on parenting styles, sensation-seeking, stress coping styles with mediation of academic skills in students with high-risk behaviors ...
Leila Amirian, Ezatolah Ghadampour, Mohammad Abasi   +2 more
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Evidence-Based Policy Strategies for Holistic Health Promotion in School-Age Children: A Synthesis from the Evaluation of the Smart Love, Smart Parenting Program in Nan Province

International Journal of Child Development and Mental Health
The objective of this research was to evaluate the effectiveness of the “Smart Love, Smart Parenting” Program in enhancing parenting skills and multiple intelligence in school-aged children in Nan Province.
Worinthep Chuasamran, Jintana Jandeem, Sorsuangsuda Pongkaew   +2 more
doaj  

Family UNited: piloting of a new universal UNODC family skills programme to improve child mental health, resilience and parenting skills in Indonesia and Bangladesh. [PDF]

Int J Ment Health Syst, 2023
Haar K, El-Khani A, Narotama N, Hussain A, Fitri E, Badrujaman A, Wahyuni E, Naheeaan SM, Yassine A, Maalouf W.   +9 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

The mediating effects of self-concept on the relationship between parenting styles and young children’s social problem-solving in Türkiye

Frontiers in Psychology
The aim of this study was to investigate the associations between parenting styles, young children’s social problem-solving skills, and the mediating role of self-concept in a sample of 200 Turkish preschoolers aged 48–72 months, with an equal ...
Ahmet Ayık, Türker Sezer, Sinan Koçyiğit   +2 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source