Results 81 to 90 of about 261,891 (305)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Correlation between parenting styles and social communication in children with hearing impaired

Liaquat Medical Research Journal
This study aimed to find the correlation between parenting style and social communication in children with hearing impairment. In this correlational study Minnesota Social skills checklist for Deaf/ hard of Hearing children and Parenting Style ...
Samia Sharif, Aleena Irum, Hafsa Noreen, Hajra Masood, Hina Sameeullah   +4 more
doaj   +1 more source

Evaluation of the Ballyfermot Strengthening Families Programme. [PDF]

, 2010
The Strengthening Families Programme (SFP) is an internationally recognised parenting and family skills initiative for high-risk families. It was developed by Dr.
Howley, Derval, Kavanagh, Mick
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Parenting Styles and the Development of Socio-Emotional Regulation Skills in Preschool Children

Journal of Psychometric Research
The study employed descriptive survey design to investigate the Parenting Styles and the Development of Socio-Emotional Regulation Skills of Preschool Children.
Rahmatallahi Taiye Ojibara
doaj   +1 more source

Acceptability and feasibility of peer assisted supervision and support for intervention practitioners: a Q-methodology evaluation [PDF]

, 2015
Evidence-based interventions often include quality improvement methods to support fidelity and improve client outcomes. Clinical supervision is promoted as an effective way of developing practitioner confidence and competence in delivery; however ...
A Steckler, B McKeown, B Tony, Birgit Schroeter, CE Watkins, D Sexton, Department of Health. National Health Service Management Executive, DL Fixsen, EF Counselman, FM Cheater, GA Aarons, GA Aarons, GX Ayala, I Berggren, J Davy, J Haines, Kerri E. McPherson, Kirsty Wiseman, Matthew R. Sanders, MR Sanders, MR Sanders, MR Sanders, MR Sanders, MR Sanders, MR Sanders, P Craig, P Karoly, R Baker, RM Cross, S Watts, S Wheeler, SK Schoenwald, SK Schoenwald, SK Schoenwald, SM Breitenstein, SR Brown, SW Henggeler, T Mazzucchelli, V Absalom-Hornby, Victoria Troy, VJ Pitt, W Stephenson   +41 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

FILIAL THERAPY UNTUK MENURUNKAN STRESS PENGASUHAN PADA IBU DENGAN ANAK YANG TERDIAGNOSA AUTISM SPECTRUM DISORDER [PDF]

Parents with children diagnosed with autism are vulnerable to parenting stress. Stress in parents occurs because of different demands from the environment and the resources and coping mechanisms that parents have to change their children to their ...
Yuliani, Sri Retno
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