Results 71 to 80 of about 134,193 (302)
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Cultural Perspective on Parenting, Trait Emotional Intelligence and Mental Health in Taiwanese Children [PDF]
, 2017 The current study aims to clarify the associations as well as the pathways through which parenting and children's emotional intelligence (EI) may influence children's mental health with a cross-sectional sample of 675 school pupils (fourth grade, mean ...
Feng, J.Y. +6 more
core +1 more source
The influence of parenting style on health related behavior of children : findings from the ChiBS study [PDF]
, 2014 Objective: Exploring associations between parenting behavior and children's health related behavior including physical activity, sedentary behavior, diet and sleep. Methods: We recruited 288 parents and their children (6-12y old).
De Henauw, Stefaan +4 more
core +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
A formal evaluation of the performance of different corporate styles in stable and turbulent environments [PDF]
The notion of "parenting styles", introduced by Goold, Campbell and Alexander, has been widely acknowledged by the Corporate Strategy literature as a good broad description of the different ways in which corporate managers choose to manage and organize ...
Caldart, Adrian A., Ricart, Joan E.
core
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Educational Process: International JournalBackground/purpose. This study aimed to identify the prevailing parenting styles in the Bekaa region in Lebanon from the parents’ perspective and to examine the relationship between these styles and parents’ educational level, income level, age, and ...
Shakiba Daoud +2 more
doaj +1 more source
فصلنامه خانواده پژوهی, 2016 The purpose of the present research is to study healthy and unhealthy perfectionism as well as type A personality based on different parenting styles.
مریم جهان بخش +2 more
doaj