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This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter+8 more
wiley +1 more source
This article describes the development of the Parenting Premmies Support Program, a mobile health intervention designed to support mothers during the transitional time following their preterm infant’s discharge from hospital.
Kendall George+3 more
doaj +1 more source
The increasing happiness of US parents [PDF]
Previous research suggests that parents may be less happy than non-parents. We critically assess the literature and examine parents’ and non-parents’ happiness-trends using the General Social Survey (N = 42,298) and DDB Lifestyle Survey (N = 75,237).
Herbst, Chris M., Ifcher, John
core +1 more source
A qualitative study into parental mediation of adolescents' internet use [PDF]
The vast majority of studies on parental mediation are quantitative by nature, which leads to a lack of in-depth understanding of how parents define and perform their role as socializing agents in this area. The present study offers new insights into how
Heirman, Wannes+3 more
core +2 more sources
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Background Childhood obesity is a global public health concern. In Ireland, the age standardized prevalence rates for obesity in children and adolescents are about 1% higher than the average for countries in the WHO European Region.
Claire O’Dwyer+9 more
doaj +1 more source
Patients’ and Caregivers’ Experiences Navigating the Burden of Atopic Dermatitis in Argentina
Background and Objectives: Little is known about patients’ and caregivers’ experiences with atopic dermatitis (AD) in Argentina, so a survey was administered to learn more.
Korey Capozza+4 more
doaj +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Patients with spina bifida (SB) face an increased risk of infection due to frequent exposure to medical procedures and visits to healthcare centers, including rehabilitation centers.
O.R. Boyarchuk+2 more
doaj +1 more source
Guideline on the diagnosis and treatment of primary idiopathic clubfoot
— A delegation of 6 pediatric orthopedic surgeons from the Dutch Orthopedic Association (NOV) and 2 members of the board of the Dutch Parents’ Association for children with clubfoot created the guideline "The diagnosis and treatment of primary idiopathic
Arnold T Besselaar+9 more
doaj +1 more source