Results 81 to 90 of about 4,477,114 (193)

Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications

Cell Proliferation, Volume 58, Issue 10, October 2025.
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su, Yanlin Li, Zihao Zhou, Bing Feng, Haiming Chen, Guangjuan Zheng   +5 more
wiley   +1 more source

Traditional Chinese Medicinal Herbs for Treating Post‐Ischemic Stroke Cognitive Impairment Insights From Frequency and Association Analysis

Brain and Behavior, Volume 15, Issue 9, September 2025.
This analysis highlights key herbs and their interactions, suggesting significant implications for further research into their efficacy and safety for stroke rehabilitation. ABSTRACT Background This study analyzes medicinal herbs in Traditional Chinese Medicine (TCM) formulations for post‐ischemic stroke cognitive impairment, identifying key herbs ...
Yixia Li, Wenqi Huang, Jing Sun, Wenjuan Li   +3 more
wiley   +1 more source

The clarification of two hydroxylation steps in the conversion of cholesterol to OSW‐1 in Ornithogalum saundersiae

Plant Biotechnology Journal, Volume 23, Issue 9, Page 4030-4043, September 2025.
Summary OSW‐1 is a cholestane saponin uniquely produced in Ornithogalum saundersiae and exhibits a potential antitumor activity. The enzymes responsible for OSW‐1 biosynthesis in O. saundersiae, however, remain unclear. Herein, cholesterol was confirmed to be the precursor of OSW‐1 using stable‐isotope labeling method.
Shu‐Yue Zhang, Jian‐Qiang Kong
wiley   +1 more source

EVALUATION OF ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF PARIS POLYPHYLLA SM.

Asian Journal of Pharmaceutical and Clinical Research, 2017
  Objectives: Paris polyphylla Sm. is a very important anti-cancerous plant species found in the Himalayan region of India. The present study was carried out to determine the phenolic and flavonoid content, antioxidant and antimicrobial activity of its rhizome.Methods: Antioxidant activity of rhizome extract was evaluated through 2,2-diphenyl-1 ...
Homsingli Mayirnao, Arbeen Ahmad Bhat
openaire   +2 more sources

Population Genetic Diversity and Species Distribution Evaluation of Bletilla striata (Orchidaceae) in Southwest China Using SSR Markers

Ecology and Evolution, Volume 15, Issue 8, August 2025.
These findings provide a scientific basis for conserving and sustainably utilizing Bletilla striata germplasm. By predicting future distribution shifts under climate change, this research offers critical insights for dynamic monitoring and conservation strategy development, holding significant theoretical and practical value for biodiversity ...
Liangliang Luo, Qian Wang, Xiaolan Li, Delin Xu, Huan Hu   +4 more
wiley   +1 more source

Integrated multi-omics analysis reveals the polyphyllins biosynthesis in Paris polyphylla var. yunnanensis across different growth years

Industrial Crops and Products
Growth duration significantly influences the active ingredient content of Paris polyphylla var. yunnanensis (Franch.) Hand.-Mazz, a valuable perennial Chinese medicinal herb.
Xiaoye Zhang, Jia Chen, Qi Qiang, Ping Xu, Guowei Zheng   +4 more
doaj   +1 more source

Steroid saponins from Paris polyphylla Sm.-supplement.

Chemical and Pharmaceutical Bulletin, 1982
Previously, four steroid glycosides (Pa-d) were isolated from the rhizomes of Paris polyphylla SM. and characterized. In a continuation of our studies on this plant, a further five new steroid glycosides (1, 2, 12, 14 and 16) together with three known compounds (13, 18 and 19 ; the latter two have been obtained synthetically as acetyl derivatives) have
MIYAMURA, MITSUHIKO, NAKANO, KIMIKO, NOHARA, TOSHIHIRO, TOMIMATSU, TOSHIAKI, KAWASAKI, TOSHIO   +4 more
openaire   +2 more sources

ElixirSeeker: A Machine Learning Framework Utilizing Fusion Molecular Fingerprints for the Discovery of Lifespan‐Extending Compounds

Aging Cell, Volume 24, Issue 8, August 2025.
ElixirSeeker is a machine learning architecture based on a phenotype‐driven drug discovery approach to screen lifespan‐extending compounds. By integrating molecular fingerprints, ElixirSeeker could maximize feature capture of lifespan‐extending compounds.
Yan Pan, Hongxia Cai, Fang Ye, Wentao Xu, Zhihang Huang, Jingyuan Zhu, Yiwen Gong, Yutong Li, Anastasia Ngozi Ezemaduka, Shan Gao, Shunqi Liu, Guojun Li, Hao Li, Jing Yang, Junyu Ning, Bo Xian   +15 more
wiley   +1 more source

A roadmap to sustainable management of commercial medicinal and aromatic plants, fungi, and lichens in Nepal

Conservation Biology, Volume 39, Issue 4, August 2025.
Abstract Thousands of plants, fungi, and lichen species are traded every year. Although sustainable use is critical for livelihoods and biodiversity conservation, insufficient data prevent detailed sustainability assessments for most species. How can the sustainability of trade in such data‐deficient species be enhanced?
Carsten Smith‐Hall, Dipesh Pyakurel, Thorsten Treue, Mariève Pouliot, Suresh Ghimire, Anastasiya Timoshyna, Henrik Meilby   +6 more
wiley   +1 more source

An Updated DNA Barcoding Tool for Aloe Vera and Related CITES‐Regulated Species

Conservation Letters, Volume 18, Issue 4, July/August 2025.
ABSTRACT DNA barcoding has revolutionized the identification of illegally traded material of endangered species as it overcomes the lack of resolution encountered with morphological identification. Nonetheless, in recently evolved and highly diverse clades, such as the relatives of Aloe vera, the lack of interspecific sequence variation in standardized
Yannick Woudstra, Paul Rees, Solofo E. Rakotoarisoa, Nina Rønsted, Caroline Howard, Olwen M. Grace   +5 more
wiley   +1 more source