Results 111 to 120 of about 196,808 (340)

Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

Neurobiology of Disease, 2014
Exercise has been shown to be beneficial for Parkinson's disease (PD). A major interest in our lab has been to investigate how exercise modulates basal ganglia function and modifies disease progression.
William A. Toy, Giselle M. Petzinger, Brian J. Leyshon, Garnik K. Akopian, John P. Walsh, Matilde V. Hoffman, Marta G. Vučković, Michael W. Jakowec   +7 more
doaj  

Adiponectin paradox as a therapeutic target of the cancer evolvability in aging

Neoplasia: An International Journal for Oncology Research, 2021
Recent study suggests that protofibril-formation of amyloidogenic proteins (APs) might be involved in evolvability, an epigenetic inheritance of multiple stresses, in various biological systems.
Yoshiki Takamatsu, Gilbert Ho, Ryoko Wada, Satoshi Inoue, Makoto Hashimoto   +4 more
doaj  

Recent Advances in Stimuli‐Responsive Materials and Soft Robotic Actuators for Bioelectronic Medicine

Advanced Materials, EarlyView.
This review explores the integration of responsive materials and soft robotic actuators with implantable electronics to address key challenges in bioelectronic medicine. By enabling shape actuation, these technologies improve deployment, adaptability, and accuracy in minimally invasive procedures.
Chaoqun Dong, George G. Malliaras
wiley   +1 more source

Unloading and shortening reactions in Parkinson's disease. [PDF]

, 1978
Ronald W. Angel, Peter A. LeWitt
openalex   +1 more source

Smart Dust for Chemical Mapping

Advanced Materials, EarlyView.
This review article explores the advancement of smart dust networks for high‐resolution spatial and temporal chemical mapping. Comprising miniature, wireless sensors, and communication devices, smart dust autonomously collects, processes, and transmits data via swarm‐based communication.
Indrajit Mondal, Hossam Haick
wiley   +1 more source

Differences in prognosis and underuse of adjuvant chemotherapy between elderly and non‐elderly patients in stage III colorectal cancer

Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 91-101, January 2023., 2023
This study analyzed data from consecutive patients with stage III colorectal cancer following curative resection and examined the reason for not introducing adjuvant chemotherapy (AC) and the differences in prognosis between completed and incomplete AC in elderly and non‐elderly patients.
Takuya Shiraishi, Hiroomi Ogawa, Ikuma Shioi, Naoya Ozawa, Katsuya Osone, Takuhisa Okada, Makoto Sohda, Ken Shirabe, Hiroshi Saeki   +8 more
wiley   +1 more source

Advances in Neurology, vol 5 (Second Canadian-American Conference on Parkinson's Disease) [PDF]

, 1974

openalex   +1 more source

Modification of Metal Microelectrodes with Vertical Graphene Structure for Enhanced Electrochemical Detection of Dopamine

Advanced Materials Interfaces, EarlyView.
In this article, vertical graphene‐modified microelectrodes (VGMEs) are fabricated by modifying vertical graphene on different types of metal microelectrodes (Au, Ti, Ag, and W) for enhanced electrochemical detection of DA. Moreover, the sensing performance on dopamine concentrations is explored with different electrochemical methods, including EIS, CV,
Lukang Gao, Shuang Huang, Xiaotong Li, Zhengjie Liu, Xinshuo Huang, Yan Li, Hui‐jiuan Chen, Xudong Lin, Jing Liu, Xi Xie   +9 more
wiley   +1 more source

Plasma level of alpha-synuclein oligomers as a biomarker for isolated rapid eye movement sleep behavior disorder diagnosis and progression: a prospective cohort study

Frontiers in Neurology
BackgroundAlpha-synuclein oligomers (o-α-syn) are pivotal in the pathogenesis of α-synucleinopathy. Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) serves as an early indicator of the disease, offering insights into disease mechanisms ...
Chao Ying, Chao Ying, Chao Ying, Chao Ying, Hui Zhang, Ting Wang, Yuan Li, Wei Mao, Songnian Hu, Songnian Hu, Songnian Hu, Songnian Hu, Lifang Zhao, Lifang Zhao, Yanning Cai, Yanning Cai, Yanning Cai, Yanning Cai, Yanning Cai   +18 more
doaj   +1 more source

Early manifestation of depressive‐like behavior in transgenic mice that express dementia with Lewy body‐linked mutant β‐synuclein

Neuropsychopharmacology Reports, 2018
Aim We previously generated transgenic (Tg) mice that expressed P123H β‐synuclein (βS), a dementia with Lewy body‐linked mutant βS. Notably, these mice recapitulated neurodegenerative features of Lewy body disease, reflected by motor dysfunction, greater
Masayo Fujita, Yoko Hagino, Yukio Takamatsu, Yuka Shimizu, Yoshiki Takamatsu, Kazutaka Ikeda, Makoto Hashimoto   +6 more
doaj   +1 more source