Results 91 to 100 of about 5,338,575 (282)

Applications of the European Parkinson's Disease Association sponsored Parkinson's Disease Composite Scale (PDCS).

, 2019
This study was addressed to determine the presence of Parkinson disease (PD) manifestations, their distribution according to motor subtypes, and the relationships with health-related quality of life (QoL) using the recently validated European Parkinson's
Rodriguez-Blazquez C, Martinez-Martin P, Hurtado González, Carlos Alberto, Chaudhuri KR, Radicati FG, PDCS European Study Group, Stocchi F, Balestrino R   +7 more
core   +2 more sources

Bringing Advanced Therapies for Parkinson's Disease to the Clinic [Elektronisk resurs] : The Scientist's Perspective

, 2021
After many years of preclinical development, cell and gene therapies have advanced from research tools in the lab to clinical-grade products for patients, and today they constitute more than a quarter of all new Phase I clinical trials for Parkinson's ...
Tomishima, Mark,, Kirkeby, Agnete,, Lund University.   +2 more
core   +1 more source

Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd, Tyler Hamby, Carlo Sacdalan, Somchai Sriplienchan, Pathariya Promensa, Luxenaree Poonpitak, Netsiri Dumrongpisutikul, Eugène Kroon, Sandhya Vasan, Robert Paul, Ferron O'Campo, Lydie Trautmann, Phillip Chan, Serena Spudich, on behalf of the RV254/SEARCH 010 Study Team, Julie Ake, Sandhya Vasan, Lydie Trautmann, Merlin Robb, Trevor Crowell, Donn Colby, Diane Bolton, Shelly Krebs, Leigh Ann Eller, Morgane Rolland, Rasmi Thomas, Dominic Paquin Proulx, Suteeraporn Pinyakorn, Tyler Hamby, Mark de Souza, Ellen Turk, Amber Moodley, Gerald Quarles, Jintanat Ananworanich, Denise Hsu, Victoria Polonis, Nelson Michael, Sheila Peel, COL Eric Garges, Alexandra Schuetz, Siriwat Akapirat, Bessara Nantapinit, Pornsuk Visudhiphan, Saowanit Getchalarat, Nampueng Churikanont, Sangsulee Thamakaison, Somchai Sriplienchan, Carlo Sacdalan, Pathariya Promsena, Luxe‐naree Poonpitak, Eugene Kroon, Nitiya Chomchey, Jintana Intasan, Varaporn Pothipala, Ferron Ocampo, Nittaya Phanuphak, Nipat Teeratakulpisan, Yuwaree Pichitchok, Anchalee Avihingsanon, Opass Putcharoen, Kiat Ruxrungtham, Thanyawee Puthanakit, Sopark Manasnayakorn, Phandee Watanaboonyongcharoen, Rungsun Rerknimitr, Irini Sereti, Daniel Douek, Eli Bortiz, Frank Maldarelli, Mary Kearney, Serena Spudich, Phillip Chan, Lishomwa Ndhlovu, Guinevere Li, Michael Corley, Victor Valcour, Peter Hunt, Jacob Estes, Afam Okoye, Jeff Lifson, Claire Deleage, Nicolas Chomont, Andres Finzi, Lyle McKinnon, Henrik Zetterberg, Robert Siliciano, Robert Paul, Julie Mannarino, Jonathan Li, John Mellors, Josh Cytkor, Dan Barouch, Michael Seaman, Boris Juelg, Alex Shalek, Timothy Schacker, Ashley Haase, Mario Stevenson, Wenjun Li, Arthur Kim, Sharon Lewin, Adam Carrico, Susana Valente, Fred Hutchinson, Josh Schiffer, Guido Ferrari, Beau Ances, Alberto Bosque, Katharine Bar, Killian Pohl, David Ho, Yaoxing Huang, Michael Busch, Mohamed Abdel‐Mohsen, Johanna Gostner, Brian Agan, Fatah Kashanchi, Greg Laird, Kathryn Holroyd   +118 more
wiley   +1 more source

Self-management education for persons with Parkinson's disease and their care partners [Elektronisk resurs] : a quasi-experimental case-control study in clinical practice

, 2020
Background Parkinson's disease is a neurodegenerative condition with both physical and mental consequences that affect many aspects of everyday life. Persons with Parkinson's disease and their care partners want guidance from healthcare services in order
Dizdar, Nil,, Hellqvist, Carina,, Hagell, Peter,, Kristianstad University., Sund-Levander, Marta,, Bertero, Carina,   +5 more
core   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Parkinson’s Disease [PDF]

, 2012
Parkinson's disease (PD) is the most common age-related motoric neurodegenerative disease initially described in the 1800's by James Parkinson as the 'Shaking Palsy'. Loss of the neurotransmitter dopamine was recognized as underlying the pathophysiology of the motor dysfunction; subsequently discovery of dopamine replacement therapies brought ...
Timothy R, Mhyre, James T, Boyd, Robert W, Hamill, Kathleen A, Maguire-Zeiss   +3 more
openaire   +2 more sources

Obstructive sleep apnea, periodic limb movements, and REM sleep without atonia are common in Parkinson's disease and correlate with motor symptom burden

Journal of Parkinson’s Disease
Background Sleep disturbances are prevalent and debilitating non-motor symptoms in patients with Parkinson's disease (PD). Objective This study aimed to explore sleep architecture and the prevalence of polysomnographic (PSG) sleep findings in PD ...
Matteo Carpi, Mariangela Pierantozzi, Mariana Fernandes, Natalia Manfredi, Raffaella Ludovisi, Michela Menegotti, Tommaso Schirinzi, Rocco Cerroni, Alessandro Stefani, Nicola Biagio Mercuri, Claudio Liguori   +10 more
doaj   +1 more source

Intraputamenal Infusion of Exogenous Neurturin Protein Restores Motor and Dopaminergic Function in the Globus Pallidus of MPTP-Lesioned Rhesus Monkeys

Cell Transplantation, 2008
The neurorestorative effects of exogenous neurturin (NTN) delivered directly into the putamen via multiport catheters were studied in 10 MPTP-lesioned rhesus monkeys expressing stable parkinsonism.
R. Grondin Ph.D., Z. Zhang, Y. Ai, F. Ding, A. A. Walton, S. P. Surgener, G. A. Gerhardt, D. M. Gash   +7 more
doaj   +1 more source

Optimal set of EEG features for emotional state classification and trajectory visualization in Parkinson's disease [PDF]

, 2014
In addition to classic motor signs and symptoms, individuals with Parkinson's disease (PD) are characterized by emotional deficits. Ongoing brain activity can be recorded by electroencephalograph (EEG) to discover the links between emotional states and ...
Mohamad, Khairiyah, Yuvaraj, Rajamanickam, Ibrahim, Norlinah Mohamed, Omar, Mohd Iqbal, Murugappan, Murugappan, Sundaraj, Kenneth, Palaniappan, Ramaswamy   +6 more
core   +1 more source

Founding Editorial: Neuro‐Drug Discovery

Neuro-Drug Discovery, EarlyView.
Wenbin Li
wiley   +1 more source