Results 71 to 80 of about 214,205 (284)

Platelet mitochondrial complex I and IV activities are not reliable stratification biomarkers in Parkinson's disease

Journal of Parkinson’s Disease
Background Mitochondrial dysfunction, particularly complex I (CI) deficiency, is considered an integral feature of Parkinson's disease (PD). However, recent findings indicate that widespread neuronal CI deficiency in the brain is only present in a ...
Simon Ulvenes Kverneng, Sepideh Mostafavi, Yana Mikhaleva, Gard Aasmund Skulstad Johanson, Haakon Berven, Katarina Lundervold, Geir Olve Skeie, Erika Sheard, Mona Søgnen, Solveig Af Geijerstam, Therese Vetås, Michele Brischigliaro, Erika Fernandez-Vizarra, Yamila N Torres Cleuren, Christian Dölle, Charalampos Tzoulis   +15 more
doaj   +1 more source

Psychogenic Tremor: A Video Guide to Its Distinguishing Features

Tremor and Other Hyperkinetic Movements, 2014
Background: Psychogenic tremor is the most common psychogenic movement disorder. It has characteristic clinical features that can help distinguish it from other tremor disorders.
Joseph Jankovic, Mary Ann Thenganatt
doaj   +1 more source

Atrophic Myenteric and Submucosal Neurons Are Observed in Parkinson's Disease [Elektronisk resurs]

, 2019
Aim. Parkinson's disease is often accompanied by gastrointestinal symptoms, especially constipation. Microscopic studies of the enteric nervous system and enteric neuropathy have often been performed by immunostaining in the myenteric plexa.
Englund, Elisabet,, Lund University., Ohlsson, Bodil,   +2 more
core   +1 more source

Parkinson's disease [PDF]

The Lancet, 2004
Parkinson's disease is the most common serious movement disorder in the world, affecting about 1% of adults older than 60 years. The disease is attributed to selective loss of neurons in the substantia nigra, and its cause is enigmatic in most individuals.
Samii, Ali, Nutt, John G., Ransom, Bruce R.   +2 more
openaire   +3 more sources

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Visual exploration in Parkinson's disease and Parkinson's disease dementia [PDF]

, 2013
Parkinson's disease, typically thought of as a movement disorder, is increasingly recognized as causing cognitive impairment and dementia. Eye movement abnormalities are also described, including impairment of rapid eye movements (saccades) and the ...
Archibald, Neil K., Hutton, Sam B., Burn, David J., Mosimann, Urs P., Clarke, Michael P.   +4 more
core   +1 more source

Stem Derived Dopamine Neurons Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?

, 2021
The use of stem cell derived dopamine neurons for treating patients with Parkinson's disease has now evolved to the first in human clinical trials.
Barker, Roger A,, Björklund, Anders,, Frucht, Steven J,, Svendsen, Clive N,, Lund University.   +4 more
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Resveratrol suppresses the growth and metastatic potential of cervical cancer by inhibiting STAT3Tyr705 phosphorylation

Cancer Medicine, 2020
Aberrant signal transducer and activator of transcription 3 (STAT3) signaling promotes the initiation and progression of cancer in humans by either inhibiting apoptosis or inducing cell proliferation, angiogenesis, invasion, and metastasis.
Xiaodong Sun, Qianqian Xu, Lian Zeng, Lixia Xie, Qiang Zhao, Hongxia Xu, Xuanbin Wang, Nan Jiang, Pan Fu, Ming Sang   +9 more
doaj   +1 more source