Results 101 to 110 of about 295,503 (301)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Utility of the new Movement Disorder Society clinical diagnostic criteria for Parkinson's disease applied retrospectively in a large cohort study of recent onset cases [PDF]

, 2017
Objective: To examine the utility of the new Movement Disorder Society (MDS) diagnostic criteria in a large cohort of Parkinson's disease (PD) patients.
,, Bajaj, Nin, Barker, Roger A., Ben-Shlomo, Yoav, Burn, David J., Foltynie, Tom, Grosset, Donald G., Grosset, Katherine A., Hardy, John, Lawton, Michael A., Malek, Naveed, Morris, Huw R., Williams, Nigel M., Wood, Nicholas   +13 more
core   +5 more sources

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Spreading of α-synuclein in the face of axonal transport deficits in Parkinson's disease: A speculative synthesis

Neurobiology of Disease, 2015
Parkinson's disease (PD) is mainly attributed to degeneration of dopamine neurons in the substantia nigra, but its etiopathogenesis also includes impaired protein clearance and axonal transport dysfunction, among others. The spread of α-synuclein (α-syn)
Jennifer T. Lamberts, Erin N. Hildebrandt, Patrik Brundin   +2 more
doaj   +1 more source

Inter-hemispheric EEG coherence analysis in Parkinson's disease : Assessing brain activity during emotion processing [PDF]

, 2014
Parkinson’s disease (PD) is not only characterized by its prominent motor symptoms but also associated with disturbances in cognitive and emotional functioning.
A Ariatti, A Cronin-Golomb, A Morita, A Suzuki, A Tessitore, AD Lawrence, AD Lawrence, AEB Cancelliere, AF Leuchter, AT Beck, B Pillon, BE Levin, C Dara, C Schröder, CC French, CF Lima, CL Yeager, D Bowers, D Schellberg, E Mohr, G Nolte, GG Celesia, H Cohen, H Hinrichs, H Kober, HL Chen, HM Gray, IH Gotlib, J Busk, J Mikels, J Péron, J Redondo, JA Obeso, JC Shaw, JF Caekebeke, JJ Gross, JM Savitt, JT Yip, K Dujardin, K Sergerie, Kenneth Sundaraj, KH Kim, Khairiyah Mohamad, KM Miller, LC Fonseca, M Lotze, M Murugappan, M. Murugappan, M. Satiyan, MA Guevara, MD Pell, MD Pell, MF Folstein, MI Ventura, MJ Wieser, MJ Wieser, MK Beyer, MM Hoehn, Mohd Iqbal Omar, MY Neufeld, Norlinah Mohamed Ibrahim, P Garrido-Vásquez, P Madeley, P Salgado-Pineda, PC Petrantonakis, PJ Lang, R Adolphs, R Adolphs, R Bastiaanse, R Soikkeli, R Sprengelmeyer, R Yuvaraj, R. Palaniappan, R. Yuvaraj, RA Roemer, RC Oldfield, RJ Davidson, RJR Blair, RW Thatcher, S Jerritta, S Paulmann, SK Hadjidimitriou, T Baumgartner, T Gasser, TF Newton, TP Bouchard, US Clark, Y Kan, Y Wang   +88 more
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Stereotactic Lesioning of the Thalamic Vo Nucleus for the Treatment of Writer's Cramp (Focal Hand Dystonia)

Frontiers in Neurology, 2018
Writer's cramp (focal hand dystonia) is a sporadic focal dystonia that affects a specific part of the upper limb causing excessive co-contraction of antagonistic muscles.
Takeshi Shimizu, Takeshi Shimizu, Tomoyuki Maruo, Tomoyuki Maruo, Shimpei Miura, Shimpei Miura, Haruhiko Kishima, Yukitaka Ushio, Satoshi Goto   +8 more
doaj   +1 more source

The Value of Multidisciplinary Care in Parkinson\u27s Disease [PDF]

, 2003
Educational Objectives 1. To recognize the signs and symptoms of Parkinson\u27s disease (PD). 2. To identify key treatment and management strategies for PD. 3.
Baron, Mark, Hirsch, Miriam
core   +1 more source

Parkin function in Parkinson's disease [PDF]

, 2018
Parkinson's disease (PD) is the second most common neurodegenerative disease, and is characterized by involuntary shaking, muscle rigidity, and the progressive loss of dopaminergic neurons.
Arkinson, Connor, Walden, Helen
core   +1 more source