Results 121 to 130 of about 5,005,064 (282)

New pharmacological treatments of Parkinson's disease

, 2020
Parkinsonism is a clinical syndrome that consists of rigidity, resting tremor, bradykinesia and postural instability. The prototypical parkinsonian disease is Parkinson's disease.
Famakinwa, Abisola
core  

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Integrated molecular landscape of Parkinson's disease [PDF]

, 2017
Parkinson's disease is caused by a complex interplay of genetic and environmental factors. Although a number of independent molecular pathways and processes have been associated with familial Parkinson's disease, a common mechanism underlying especially ...
Martens, G.J.M., Gasser, T., Visser, J. E., Isacson, O., Sharma, M., Visser, J.E., Poelmans, G.J.V., Martens, M.B., Klemann, C.J.H.M., Poelmans, G., Martens, G. J. M., Martens, M. B., Klemann, C. J. H. M.   +12 more
core   +2 more sources

Stereotactic Lesioning of the Thalamic Vo Nucleus for the Treatment of Writer's Cramp (Focal Hand Dystonia)

Frontiers in Neurology, 2018
Writer's cramp (focal hand dystonia) is a sporadic focal dystonia that affects a specific part of the upper limb causing excessive co-contraction of antagonistic muscles.
Takeshi Shimizu, Takeshi Shimizu, Tomoyuki Maruo, Tomoyuki Maruo, Shimpei Miura, Shimpei Miura, Haruhiko Kishima, Yukitaka Ushio, Satoshi Goto   +8 more
doaj   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

Levodopa Fractionation in Parkinson's Disease

, 2014
Background:Fractionation of daily levodopa dosage is one strategy to manage the almost inevitable development of symptom fluctuations in Parkinson's disease (PD).
Nyholm, Dag,, Stepien, Victoria,
core   +1 more source

Parkinson′s disease

Annals of Indian Academy of Neurology, 2011
Behari, Madhuri, Bhattacharyya, Kalyan Brata, Borgohain, Rupam, Das, Shyamal Kumar, Ghosh, Bhaskar, Kishore, Asha, Krishnan, Syam, Mridula, K Rukmini, Muthane, Uday, Pal, Pramod Kumar, Sankhla, Charulata, Shukla, Garima   +11 more
openaire   +5 more sources

Palliative care for Parkinson’s disease: suggestions from a council of patient and carepartners

npj Parkinson's Disease, 2017
In 2015, the Parkinson’s Disease Foundation sponsored the first international meeting on Palliative Care and Parkinson’s disease and the Patient Centered Outcomes Research Institute funded the first comparative effectiveness trial of palliative care for ...
Kirk Hall, Malenna Sumrall, Gil Thelen, Benzi M. Kluger, on behalf of the 2015 Parkinson’s Disease Foundation sponsored “Palliative Care and Parkinson’s Disease” Patient Advisory Council   +4 more
doaj   +1 more source

Pathogenesis and pathophysiology of functional (psychogenic) movement disorders

Neurobiology of Disease, 2019
Functional movement disorders (FMDs), known over time as “hysteria”, “dissociative”, “conversion”, “somatoform”, “non-organic” and “psychogenic” disorders, are characterized by having a voluntary quality, being modifiable by attention and distraction but
José Fidel Baizabal-Carvallo, Mark Hallett, Joseph Jankovic   +2 more
doaj   +1 more source