Results 231 to 240 of about 9,647,508 (315)

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie   +18 more
wiley   +1 more source

Parkinson's Disease as Illness Anxiety Disorder: A Rare Case Report. [PDF]

open access: yesClin Case Rep
Fatahi R   +4 more
europepmc   +1 more source

Effects of Cognitive Training on Balance and Motor Symptoms in Parkinson's Disease: An Exploratory Randomized Controlled Trial [PDF]

open access: bronze
Aída Arroyo-Ferrer   +5 more
openalex   +1 more source

Spatially Resolved Mapping of Voltage‐Gated Proton Channel Activity Reveals Delayed Proton Transport in Local Microenvironments

open access: yesAdvanced Science, EarlyView.
A revolutionary imaging platform integrating quantitative single‐molecule photobleaching with ratiometric fluorescence probes enables high‐throughput (≈2300 individually resolvable channels) mapping of individual proton channels in a large field (≈3000 µm2), overcoming the spatial and temporal limitations of conventional electrophysiology.
Jiahua Zhuang   +5 more
wiley   +1 more source

Retinal Neurovascular Signatures in Parkinson's Disease. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Zhu W   +9 more
europepmc   +1 more source

Accurate Generation of Conformational Ensembles for Intrinsically Disordered Proteins with IDPFold

open access: yesAdvanced Science, EarlyView.
In brief: IDPFold predicts the conformational ensembles of intrinsically disordered proteins (IDPs) from their amino acid sequences. The atomic structures generated by IDPFold offer crucial insights into the intricate relationship between IDP structures and their diverse biological functions.2 Abstract Intrinsically disordered proteins (IDPs) play ...
Junjie Zhu   +10 more
wiley   +1 more source

Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease.

open access: yesNew England Journal of Medicine, 1998
P. Limousin   +6 more
semanticscholar   +1 more source

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