Results 51 to 60 of about 9,561,546 (382)

Laserlight visual cueing device for freezing of gait in Parkinson's disease: a case study of the biomechanics involved [PDF]

open access: yes, 2015
Background: Freezing of gait (FOG) is a serious gait disorder affecting up to two-thirds of people with Parkinson's disease (PD). Cueing has been explored as a method of generating motor execution using visual transverse lines on the floor.
B. Evans   +7 more
core   +1 more source

The Shaking Palsy of the Larynx—Potential Biomarker for Multiple System Atrophy: A Pilot Study and Literature Review

open access: yesFrontiers in Neurology, 2019
In its early stages multiple system atrophy (MSA), a neurodegenerative movement disorder, can be difficult to differentiate from idiopathic Parkinson's disease (PD), and emphasis has been put on identifying premotor symptoms to allow for its early ...
Tobias Warnecke   +9 more
doaj   +1 more source

Uncovering Essential Tremor Genetics: The Promise of Long-Read Sequencing

open access: yesFrontiers in Neurology, 2022
Long-read sequencing (LRS) technologies have been recently introduced to overcome intrinsic limitations of widely-used next-generation sequencing (NGS) technologies, namely the sequencing limited to short-read fragments (150–300 base pairs).
Luca Marsili   +4 more
doaj   +1 more source

PhoneMD: Learning to Diagnose Parkinson's Disease from Smartphone Data

open access: yes, 2018
Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However, misdiagnoses are common.
Karlen, Walter, Schwab, Patrick
core   +1 more source

What contributes to depression in Parkinson's disease? [PDF]

open access: yes, 2001
Background: Depression is a common problem in patients with Parkinson's disease, but its mechanism is poorly understood. It is thought that neurochemical changes contribute to its occurrence, but it is unclear why some patients develop depression and ...
Jahanshahi, M., Quinn, N.P., Schrag, A.
core   +1 more source

Rehabilitation and Parkinson’s Disease [PDF]

open access: yesParkinson's Disease, 2012
Early after the turn of the century, much excitement was generated by the reports of Tillerson et al. [1, 2] that exercise appeared to protect against neuronal degeneration in rodent models of toxin-induced parkinsonism. Such findings, coupled with epidemiologic suggestions that persons with a history of moderate to vigorous exercise may have a ...
Gammon M. Earhart   +3 more
openaire   +5 more sources

Quantitative analysis of language production in Parkinson's disease using a cued sentence generation task [PDF]

open access: yes, 2012
The present study examined language production skills in Parkinson's disease (PD) patients. A unique cued sentence generation task was created in order to reduce demands on memory and attention.
Corthals, Paul   +4 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse

open access: yesNeurobiology of Disease, 2014
Parkinson's disease (PD) is a neurodegenerative disorder classically characterized by the death of dopamine (DA) neurons in the substantia nigra pars compacta and by intracellular Lewy bodies composed largely of α-synuclein.
Tonya N. Taylor   +17 more
doaj   +1 more source

Additional Physical Interventions to Conventional Physical Therapy in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Clinical Trials [PDF]

open access: yes, 2020
Parkinson's disease (PD) represents the second most common neurodegenerative disease. Currently, conventional physical therapy is complemented by additional physical interventions with recreational components, improving different motor conditions in ...
Heredia Rizo, Alberto-Marcos   +4 more
core   +2 more sources

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