Results 51 to 60 of about 9,423,446 (404)

Mild Cognitive Impairment in Parkinson’s Disease: A Review of Current Concepts

open access: yesNeurology Research International, 2013
Mild Cognitive Impairment in Parkinson’s Disease (PD-MCI) is common and may be associated with accelerated progression to dementia. Considering the importance of this emerging entity, new diagnostic criteria have recently been proposed. Early recognition
Natalie C. Palavra   +2 more
doaj   +1 more source

The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case-control study using the UK General Practice Research Database. [PDF]

open access: yes, 2013
AIMS: To investigate whether the use of carbamazepine is associated with reduced risk of Parkinson's disease. METHODS: We conducted a population-based, matched case-control study of patients randomly selected from the UK General Research Practice ...
Douglas, Ian, Skow, Aine, Smeeth, Liam
core   +1 more source

Rehabilitation and Parkinson’s Disease [PDF]

open access: yesParkinson's Disease, 2012
Early after the turn of the century, much excitement was generated by the reports of Tillerson et al. [1, 2] that exercise appeared to protect against neuronal degeneration in rodent models of toxin-induced parkinsonism. Such findings, coupled with epidemiologic suggestions that persons with a history of moderate to vigorous exercise may have a ...
Gammon M. Earhart   +3 more
openaire   +5 more sources

Everyday walking with Parkinson's disease: understanding personal challenges and strategies [PDF]

open access: yes, 2008
PURPOSE: This qualitative study was designed to explore the personal experience of everyday walking with Parkinson's disease (PD), the challenges and the strategies employed to compensate for difficulties, to help contextualise the scientific knowledge ...
Birleson, Angela   +7 more
core   +2 more sources

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Pain-motor integration in the primary motor cortex in Parkinson's disease [PDF]

open access: yes, 2017
In Parkinson's disease (PD), the influence of chronic pain on motor features has never been investigated. We have recently designed a technique that combines nociceptive system activation by laser stimuli and primary motor cortex (M1) activation through ...
Berardelli, Alfredo   +9 more
core   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Visual exploration in Parkinson’s disease and Parkinson’s disease dementia [PDF]

open access: yesBrain, 2013
Parkinson's disease, typically thought of as a movement disorder, is increasingly recognized as causing cognitive impairment and dementia. Eye movement abnormalities are also described, including impairment of rapid eye movements (saccades) and the fixations interspersed between them.
Michael P. Clarke   +5 more
openaire   +6 more sources

Paired-Pulse Inhibition in the Auditory Cortex in Parkinson's Disease and Its Dependence on Clinical Characteristics of the Patients

open access: yesParkinson's Disease, 2011
We aimed to determine the value of the paired-pulse inhibition (PPI) in the auditory cortex in patients with Parkinson's disease (PD) and analyze its dependence on clinical characteristics of the patients. The central (Cz) auditory evoked potentials were
Elena Lukhanina   +2 more
doaj   +1 more source

Anti-oxidants in Parkinson's disease therapy: a critical point of view [PDF]

open access: yes, 2016
Parkinson's disease (PD) is a degenerative neurological syndrome, which is characterized by the preferential death of dopaminergic (DAergic) neurons in the SubstantiaNigra.
Beltramini, Mariano   +3 more
core   +2 more sources

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