Results 91 to 100 of about 236,137 (343)

Cerebello‐Prefrontal Connectivity Underlying Cognitive Dysfunction in Spinocerebellar Ataxia Type 2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 2 (SCA2) is a hereditary cerebellar degenerative disorder, with motor and cognitive symptoms. The constellation of cognitive symptoms due to cerebellar degeneration is named cerebellar cognitive affective syndrome (CCAS), which has increasingly been recognized to profoundly impact patients' quality of life;
Ami Kumar, Ruo‐Yah Lai, Zena Fadel, Yicheng Lin, Pia Parekh, Rachel Griep, Ming‐Kai Pan, Sheng‐Han Kuo   +7 more
wiley   +1 more source

Measuring anxiety in Lewy Body Disease – Which scale to choose?

Clinical Parkinsonism & Related Disorders, 2021
Background: Anxiety is among the most prevalent mood disorders in Lewy Body Disease (LBD) (i.e., Parkinson’s disease (PD), Dementia with Lewy bodies DLB), and those at-risk for developing LBD (e.g. isolated REM Sleep Behaviour Disorder (iRBD)).
Isabel Paniak, Simon J.G. Lewis, Kaylena A. Ehgoetz Martens   +2 more
doaj  

Additional file 6: of Blood transcriptomics of drug-naĂŻve sporadic Parkinsonâ s disease patients

, 2015
List of differentially expressed genes between PD patients and controls based on PUMA. Ratios are calculated as differences in gene expression between samples of PD patients and controls, with the top up-regulated genes first. (PDF 3122 kb)
Calligaris, Raffaella, Banica, Mihaela, Roncaglia, Paola, Robotti, Elisa, Finaurini, Sara, Vlachouli, Christina, Antonutti, Lucia, Iorio, Francesco, Carissimo, Annamaria, Cattaruzza, Tatiana, Ceiner, Andrea, Lazarevic, Dejan, Cucca, Alberto, Pangher, Nicola, Marengo, Emilio, Bernardo, Diego Di, Pizzolato, Gilberto, Gustincich, Stefano   +17 more
openaire   +1 more source

Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan, Huaju Tian, Cheng Wu, Yue Zhao, Daiying Zhang, Yujie Zheng, Yuan Li, Xiaoxia Duan   +7 more
wiley   +1 more source

Botulinum Toxin for the Treatment of Hand Tremor

Toxins, 2018
The aim of this study is to review our longitudinal experience with onabotulinumtoxinA (onaBoNT-A) injections for medically refractory hand tremor. We performed a retrospective review of our database of patients treated with onaBoNT-A for hand tremor ...
Nicki Niemann, Joseph Jankovic
doaj   +1 more source

“LRRK2: Autophagy and Lysosomal Activity”

Frontiers in Neuroscience, 2020
It has been 15 years since the Leucine-rich repeat kinase 2 (LRRK2) gene was identified as the most common genetic cause for Parkinson’s disease (PD). The two most common mutations are the LRRK2-G2019S, located in the kinase domain, and the LRRK2-R1441C,
Marta Madureira, Marta Madureira, Natalie Connor-Robson, Richard Wade-Martins   +3 more
doaj   +1 more source

Classification and Prediction of Heart Diseases using Machine Learning Algorithms [PDF]

Heart disease is a serious worldwide health issue because it claims the lives of many people who might have been treated if the disease had been identified earlier. The leading cause of death in the world is cardiovascular disease, usually referred to as heart disease.
arxiv   +1 more source

Additional file 1: of Experiences of fear of falling in persons with Parkinsonâ s disease â a qualitative study

, 2018
The study-specific semi-structured interview guide. (DOCX 13Â kb)
Jonasson, Stina, Nilsson, Maria, Lexell, Jan, Carlsson, Gunilla   +3 more
openaire   +1 more source

Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan, Shravni Deshmukh, Mark Cummings, Aditi Doshi, Kourosh Rezania, Sally Freels, Gina Sawa   +6 more
wiley   +1 more source

Recent Advances in Understanding and Managing Tourette Syndrome [version 1; referees: 3 approved]

F1000Research, 2016
Tourette syndrome (TS) is a neurologic and behavioral disorder consisting of motor and phonic tics with onset in childhood or adolescence. The severity of tics can range from barely perceptible to severely impairing due to social embarrassment ...
Mary Ann Thenganatt, Joseph Jankovic
doaj   +1 more source