Results 91 to 100 of about 9,306,982 (363)

Recent Advances in Understanding and Managing Tourette Syndrome [version 1; referees: 3 approved]

F1000Research, 2016
Tourette syndrome (TS) is a neurologic and behavioral disorder consisting of motor and phonic tics with onset in childhood or adolescence. The severity of tics can range from barely perceptible to severely impairing due to social embarrassment ...
Mary Ann Thenganatt, Joseph Jankovic
doaj   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Botulinum Toxin for the Treatment of Hand Tremor

Toxins, 2018
The aim of this study is to review our longitudinal experience with onabotulinumtoxinA (onaBoNT-A) injections for medically refractory hand tremor. We performed a retrospective review of our database of patients treated with onaBoNT-A for hand tremor ...
Nicki Niemann, Joseph Jankovic
doaj   +1 more source

Additional file 10: of Blood transcriptomics of drug-naĂŻve sporadic Parkinsonâ s disease patients

, 2015
List of common genes between A9 DA neurons of the SN in the mouse and differentially expressed transcripts in the blood of PD patients according to SAM (a) and PUMA (b). (PDF 3122 kb)
Calligaris, Raffaella, Banica, Mihaela, Roncaglia, Paola, Robotti, Elisa, Finaurini, Sara, Vlachouli, Christina, Antonutti, Lucia, Iorio, Francesco, Carissimo, Annamaria, Cattaruzza, Tatiana, Ceiner, Andrea, Lazarevic, Dejan, Cucca, Alberto, Pangher, Nicola, Marengo, Emilio, Bernardo, Diego Di, Pizzolato, Gilberto, Gustincich, Stefano   +17 more
openaire   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Immunogenicity Associated with Botulinum Toxin Treatment

Toxins, 2019
Botulinum toxin (BoNT) has been used for the treatment of a variety of neurologic, medical and cosmetic conditions. Two serotypes, type A (BoNT-A) and type B (BoNT-B), are currently in clinical use. While considered safe and effective, their use has been
Steven Bellows, Joseph Jankovic
doaj   +1 more source

Update on treatments for nonmotor symptoms of Parkinson's disease—an evidence‐based medicine review

Movement Disorders, 2019
To update evidence‐based medicine recommendations for treating nonmotor symptoms in Parkinson's disease (PD).
K. Seppi, K. Ray Chaudhuri, M. Coelho, S. Fox, R. Katzenschlager, Santiago Perez Lloret, D. Weintraub, C. Sampaio, Lana Eva‐Maria Beatrice Shen‐Yang Werner Atbin Chahine Hametner Heim Lim Poewe Djamshidian‐Tehran, L. Chahine, E. Hametner, B. Heim, Shen-Yang Lim, W. Poewe, A. Djamshidian-Tehrani   +14 more
semanticscholar   +1 more source

A Novel Approach to Implementing Artificial Thalamic Neurons with Ferroelectric Transistors

Advanced Functional Materials, EarlyView.
Artificial neurons created using CMOS technology often require a large number of transistors and capacitors. This study introduces an artificial thalamic neuron that employs only five CMOS compatible ferroelectric transistors. The manufactured thalamic neuron demonstrates leaky integrate‐and‐fire‐or‐burst (LIFB) functionalities, featuring self ...
Andreas Grenmyr, Jiayuan Zhang, Jingxuan Sun, Kenta Moto, Stefan Wiefels, Seong‐Ryong Koh, Detlev Grützmacher, Qing‐Tai Zhao   +7 more
wiley   +1 more source

Additional file 4: of Blood transcriptomics of drug-naĂŻve sporadic Parkinsonâ s disease patients

, 2015
Square of the Mahalanobis distance calculated for each sample from both control and pathological class models. (PDF 3122 kb)
Calligaris, Raffaella, Banica, Mihaela, Roncaglia, Paola, Robotti, Elisa, Finaurini, Sara, Vlachouli, Christina, Antonutti, Lucia, Iorio, Francesco, Carissimo, Annamaria, Cattaruzza, Tatiana, Ceiner, Andrea, Lazarevic, Dejan, Cucca, Alberto, Pangher, Nicola, Marengo, Emilio, Bernardo, Diego Di, Pizzolato, Gilberto, Gustincich, Stefano   +17 more
openaire   +1 more source

Computer-Aided Diagnosis of Speech Disorder Signal in Parkinson’s Disease

INTERNATIONAL JOURNAL OF COMPUTERS & TECHNOLOGY, 2016
Computer-aided diagnosis (CAD) can be used as a decision support system by physicians in the diagnosis and treatmentof disordered speech especially those who specialize in neurophysiology diseases. Parkinson's disease (PD) is aprogressive disorder of the nervous system that affects movement.
Heba M. Afify, Basma Ahmed
openaire   +3 more sources