Results 111 to 120 of about 263,626 (317)
Cooperative Genome-Wide Analysis Shows Increased Homozygosity in Early Onset Parkinson's Disease [PDF]
, 2012 Parkinson's disease (PD) occurs in both familial and sporadic forms, and both monogenic and complex genetic factors have been identified. Early onset PD (EOPD) is particularly associated with autosomal recessive (AR) mutations, and three genes, PARK2 ...Heutink, Peter, Nicholas W. Wood (49276), Kilarski, Laura, Simon-Sanchez, J, Schulte, C., Heutink, P., John Hardy (23295), Morris, HR, Hardy, John, Andrew B. Singleton (178128), Laura L Kilarski, Conso, IPDG, Holmans, Peter, Holmans, P., Laura L. Kilarski (178120), John Hardy, Kilarski, Laura L., Hardy, J, Javier Simón-Sánchez (178117), Maria Martinez (87313), Schulte, Claudia, Singleton, Andrew B., Simon-Sanchez, J., Claudia Schulte, Hardy, J., International Parkinson's Disease Genomics Consortium, Kilarski, LL, Maria Martinez, Morris, H.R., Thomas Gasser, Andrew B Singleton, Nigel Williams (178133), Brown, Matthew, Brice, A, Thomas Gasser (33499), Peter Heutink, Williams, Nigel, Morris, Huw Rees, Holmans, P, Alexis Brice, Singleton, AB, Martinez, M., Kilarski, L.L., Gasser, T., Martinez, M, Gasser, T, Singleton, A.B., Claudia Schulte (125865), Nalls, MA, Holmans, Peter Alan, Nalls, M.A., Williams, N., Peter Holmans (28936), Javier Simón-Sánchez, Wood, NW, Nalls, Michael A., Schulte, C, Peter Holmans, Alexis Brice (41775), Peter Heutink (39587), Heutink, P, Wood, Nicholas W., Morris, Huw R., Williams, Nigel Melville, Brice, Alexis, Nicholas W Wood, Simon-Sanchez, Javier, Nigel Williams, Huw R. Morris (139451), Brice, A., Martinez, Maria, Michael A Nalls, Williams, N, Michael A. Nalls (113680), Wood, N.W., Wellcome Trust Case Control Consortium, Consor, WTCC, Gasser, Thomas, Huw R Morris +78 morecore +1 more sourceRelationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives
Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch +8 morewiley +1 more sourceImmunogenicity Associated with Botulinum Toxin Treatment
Toxins, 2019 Botulinum toxin (BoNT) has been used for the treatment of a variety of neurologic, medical and cosmetic conditions. Two serotypes, type A (BoNT-A) and type B (BoNT-B), are currently in clinical use. While considered safe and effective, their use has been Steven Bellows, Joseph Jankovicdoaj +1 more sourceMOESM2 of A randomized controlled efficacy study of the Medido medication dispenser in Parkinsonâ s disease
, 2019 Additional file 2. Table with secondary outcomes of EQ5D-5L, VAS, NMS-Quest.Hannink, K., Brake, L., Oonk, N.G.M., Wertenbroek, A.A., Piek, M., Vree-Egberts, L., Faber, M.J., Palen, J., Dorresteijn, L.D. +8 moreopenaire +1 more sourceEffects of dance therapy on balance, gait and neuro-psychological performances in patients with Parkinson's disease and postural instability
, 2012 Postural Instability (PI) is a core feature of
Parkinson’s Disease (PD) and a major cause of falls and disabilities. Impairment of executive functions has been called as an aggravating factor on motor performances. Dance therapy has been shown effective Paulus, Kai Stephan, Agnetti, Virgilio, Tolu, Eusebio, Deriu, Franca, De Natale, Edoardo, Sotgiu, Giovanni, Aiello, Elena +6 morecore GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou +11 morewiley +1 more sourceAdditional file 1: of Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinsonâ s disease
, 2016 Supplementary Materials and Methods. (PDF 401Â kb)Majbour, Nour, Vaikath, Nishant, van Dijk, Karin, Ardah, Mustafa, Varghese, Shiji, Vesterager, Louise, Montezinho, Liliana, Poole, Stephen, Safieh-Garabedian, Bared, Tokuda, Takahiko, Teunissen, Charlotte, Berendse, Henk, van de Berg, Wilma, El-Agnaf, Omar +13 moreopenaire +1 more sourceDifferential sialylation of serpin A1 in the early diagnosis of Parkinson's disease dementia. [PDF]
, 2012 The prevalence of Parkinson's disease (PD) increases with age. Up to 50% of PD show cognitive decline in terms of a mild cognitive impairment already in early stages that predict the development of dementia, which can occur in up to 80% of PD patients ...Hans A Kretzschmar, Manuela Neumann, Hans A. Kretzschmar (46374), Neumann, Manuela, Soininen, H., Saskia Tawfik, Hengerer, B., Herukka, Sanna-Kaisa, Kulaksiz, H., Ferger, B., Tawfik, Saskia, Steinacker, Petra, Steinacker, P., Lenter, M., Manuela Neumann (120819), Jesse, S., Lehnert, S., Kulaksiz, Hasan, Bastian Hengerer, Neumann, M., Christine A F von Arnim, Markus Otto (120832), Otto, Markus, Christine A. F. von Arnim (120817), Lucilla Parnetti (120805), Sarah Jesse (120792), Parnetti, Lucilla, Hilkka Soininen, Jahn, Olaf, Wiltfang, Jens, Hilkka Soininen (120808), Jahn, O., Petra Steinacker (120812), Tumani, Hayrettin, Lenter, Martin, Kretzschmar, Hans A., Tumani, H., Otto, M., Boris Ferger, Hayrettin Tumani, Martin Lenter, Hengerer, Bastian, Saskia Tawfik (120814), Wiltfang, J., Olaf Jahn, Lucilla Parnetti, Soininen, Hilkka, Bastian Hengerer (120831), Sanna-Kaisa Herukka, Olaf Jahn (120801), Martin Lenter (120825), von Arnim, Christine A. F., Markus Otto, von Arnim, C., Stefan Lehnert, Petra Steinacker, Hayrettin Tumani (120815), Arnim, Christine A. F. von, Hasan Kulaksiz, Ferger, Boris, Stefan Lehnert (120797), Jens Wiltfang (44073), Sanna-Kaisa Herukka (120810), Jens Wiltfang, Kretschmar, H., Parnetti, L., Hasan Kulaksiz (120823), Boris Ferger (120827), Herukka, S., Jesse, Sarah, Tawfik, S., Lehnert, Stefan, Sarah Jesse +72 morecore +1 more source
