Results 91 to 100 of about 213,535 (253)

Online cognitive monitoring technology for people with Parkinson’s disease and REM sleep behavioural disorder

npj Digital Medicine
Automated online cognitive assessments are set to revolutionise clinical research and healthcare. However, their applicability for Parkinson’s Disease (PD) and REM Sleep Behavioural Disorder (RBD), a strong PD precursor, is underexplored.
Maria Bălăeţ, Falah Alhajraf, Tanja Zerenner, Jessica Welch, Jamil Razzaque, Christine Lo, Valentina Giunchiglia, William Trender, Annalaura Lerede, Peter J. Hellyer, Sanjay G. Manohar, Paresh Malhotra, Michele Hu, Adam Hampshire   +13 more
doaj   +1 more source

Additional file 2: of The association between Parkinsonâ s disease and melanoma: a systematic review and meta-analysis

, 2015
Quality assessment of studies included in the Meta-analysis. Criterion include five parts: 1) definition of PD diagnosis; 2) validation of PD diagnosis; 3) adjustment for confounding factors; 4) source and definition of cancer diagnoses; 5) representativeness of cases. Potential total scores ranged from 0 to 9. (PDF 127 kb)
Huang, Pei, Yang, Xiao-Dong, Chen, Sheng-Di, Xiao, Qin   +3 more
openaire   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

MOESM3 of A randomized controlled efficacy study of the Medido medication dispenser in Parkinsonâ s disease

, 2019
Additional file 3. Table with secondary outcomes of UPDRS-4.
Hannink, K., Brake, L., Oonk, N.G.M., Wertenbroek, A.A., Piek, M., Vree-Egberts, L., Faber, M.J., Palen, J., Dorresteijn, L.D.   +8 more
openaire   +1 more source

Additional file 1: of The association between Parkinsonâ s disease and melanoma: a systematic review and meta-analysis

, 2015
Characteristics of studies included in the Meta-analysis. Including information of first author, year of publication, country, study design, number of patients and controls, duration of follow-up. (PDF 74 kb)
Huang, Pei, Yang, Xiao-Dong, Chen, Sheng-Di, Xiao, Qin   +3 more
openaire   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Additional file 1: of Recent advances in rehabilitation for Parkinsonâ s Disease with Exergames: A Systematic Review

, 2019
Table S1. Overview of the selected RCTs and Pilot Studies (PDF 276 kb)
Garcia-Agundez, Augusto, Folkerts, Ann-Kristin, Konrad, Robert, Caserman, Polona, Tregel, Thomas, Goosses, Mareike, GĂśbel, Stefan, Kalbe, Elke   +7 more
openaire   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Additional file 1: of Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinsonâ s disease

, 2016
Supplementary Materials and Methods. (PDF 401Â kb)
Majbour, Nour, Vaikath, Nishant, van Dijk, Karin, Ardah, Mustafa, Varghese, Shiji, Vesterager, Louise, Montezinho, Liliana, Poole, Stephen, Safieh-Garabedian, Bared, Tokuda, Takahiko, Teunissen, Charlotte, Berendse, Henk, van de Berg, Wilma, El-Agnaf, Omar   +13 more
openaire   +1 more source