Results 71 to 80 of about 263,626 (317)

A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

Nature Communications, 2020
The substantia nigra is important in neurological disease, particularly movement disorders. Here the authors provide a single cell transcriptomic atlas for the human substantia nigra.
Devika Agarwal, Cynthia Sandor, Viola Volpato, Tara M. Caffrey, Jimena Monzón-Sandoval, Rory Bowden, Javier Alegre-Abarrategui, Richard Wade-Martins, Caleb Webber   +8 more
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

MOESM2 of Prevalence and incidence of Parkinsonâ s disease and drug-induced parkinsonism in Korea

, 2019
Additional file 2: Figure S1. Sensitivity analysis. Incidence of drug-induced parkinsonism in Korea.
Han, Sola, Kim, Siin, Kim, Hyungtae, Shin, Hae-Won, Na, Kyoung-Sae, Suh, Hae Sun   +5 more
openaire   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

MOESM4 of A randomized controlled efficacy study of the Medido medication dispenser in Parkinsonâ s disease

, 2019
Additional file 4. Table with secondary outcomes of PDQ-carer.
Hannink, K., Brake, L., Oonk, N.G.M., Wertenbroek, A.A., Piek, M., Vree-Egberts, L., Faber, M.J., Palen, J., Dorresteijn, L.D.   +8 more
openaire   +1 more source

Does cueing training improve physical activity in patients with Parkinson's disease?

, 2010
Patients with Parkinson’s disease (PD) are encouraged to stay active to maintain their mobility. Ambulatory activity monitoring (AM) provides an objective way to determine type and amount of gait-related daily activities.
Lim - de Vries, L.I.I.K., Nieuwboer, Alice, Willems, A.M., Hetherington, V., Wegen, E.E.H. van, van Wegen, E.E.H., Lim, Inge, Kwakkel, Gert, Rochester, Lynn, Jones, D., Lim-de Vries, L.I.I.K., Jones, Diana, Rochester, L., van Wegen, Erwin, Baker, Katherine, Baker, K., Nieuwboer, A., Hetherington, Victoria, Willems, Anne-Marie, Kwakkel, G.   +19 more
core   +1 more source

Costs of Parkinson's Disease and Antiparkinsonian Pharmacotherapy: An Italian Cohort Study [PDF]

, 2010
Objective: Antiparkinsonian pharmacotherapy is costly and the determinants of drug costs in Parkinson's disease (PD) have been poorly investigated. The objective of this study was to investigate the costs of PD and antiparkinsonian drugs in an Italian ...
Katia Longo, Oertel, Wolfgang H., Bötzel, Kai, Yaroslav Winter, Karla Eggert, Paolo Barone, Balzer-Geldsetzer, Monika, Kai Boetzel, Dodel, Richard, Longo, Katia, Jens P. Reese, Wolfgang H. Oertel, Sonja von Campenhausen, Giuseppe Spiga, Campenhausen, Sonja von, Winter, Yaroslav, Richard Dodel, Reese, Jens P., Barone, Paolo, Spiga, Giuseppe, Eggert, Karla, Monika Balzer-Geldsetzer   +21 more
core   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Striatal Vulnerability in Huntington’s Disease: Neuroprotection Versus Neurotoxicity

Brain Sciences, 2017
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease caused by the expansion of a CAG trinucleotide repeat encoding an abnormally long polyglutamine tract (PolyQ) in the huntingtin (Htt) protein.
Ryoma Morigaki, Satoshi Goto
doaj   +1 more source

Additional file 1: of LRRK2 contributes to monocyte dysregulation in Parkinsonâ s disease

, 2019
Supplementary materials and methods. (PDF 1185 kb)
Bliederhaeuser, Corinna, Zondler, Lisa, Grozdanov, Veselin, Ruf, Wolfgang, Brenner, David, Melrose, Heather, Bauer, Peter, Ludolph, Albert, Gillardon, Frank, Kassubek, Jan, Weishaupt, Jochen, Danzer, Karin   +11 more
openaire   +1 more source