Results 51 to 60 of about 457,449 (311)

Additional file 2: of Meta-analysis of risk factors for Parkinsonâ s disease dementia

, 2016
Details of the study results. This file provided detailed results of meta-analysis of each risk factor. (DOCX 159 kb)
Xu, Yaqian, Yang, Jing, Shang, Huifang
openaire   +1 more source

Dissociating Explicit and Implicit Timing in Parkinson\u2019s Disease Patients: Evidence from Bisection and Foreperiod Tasks [PDF]

, 2018
A consistent body of literature reported that Parkinson\u2019s disease (PD) is marked by severe deficits in temporal processing. However, the exact nature of timing problems in PD patients is still elusive.
Capizzi, Mariagrazia, Correa, \uc1ngel, Di Giacopo, Raffaella, Mioni, Giovanna, Stablum, Franca, Vallesi, Antonino   +5 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Axonal Modulation of Striatal Dopamine Release by Local γ-Aminobutyric Acid (GABA) Signalling

Cells, 2021
Striatal dopamine (DA) release is critical for motivated actions and reinforcement learning, and is locally influenced at the level of DA axons by other striatal neurotransmitters. Here, we review a wealth of historical and more recently refined evidence
Bradley M. Roberts, Emanuel F. Lopes, Stephanie J. Cragg   +2 more
doaj   +1 more source

Additional file 1: of Surgical outcomes of spinal fusion for osteoporotic thoracolumbar vertebral fractures in patients with Parkinsonâ s disease: what is the impact of Parkinsonâ s disease on surgical outcome?

, 2019
The assessment Scale Proposed by the Japanese Orthopaedic Association. The Japanese Orthopaedic Association Scoring system (JOA score) consists of 2 categories (subjective and objective symptoms), ranging from 0 (worst condition) to 15 (best condition). (DOCX 22 kb)
Watanabe, Kei, Katsumi, Keiichi, Ohashi, Masayuki, Shibuya, Yohei, Izumi, Tomohiro, Hirano, Toru, Endo, Naoto, Kaito, Takashi, Yamashita, Tomoya, Fujiwara, Hiroyasu, Nagamoto, Yukitaka, Matsuoka, Yuji, Suzuki, Hidekazu, Nishimura, Hirosuke, Terai, Hidetomi, Tamai, Koji, Tagami, Atsushi, Yamada, Syuta, Adachi, Shinji, Yoshii, Toshitaka, Ushio, Shuta, Harimaya, Katsumi, Kawaguchi, Kenichi, Yokoyama, Nobuhiko, Oishi, Hidekazu, Doi, Toshiro, Kimura, Atsushi, Inoue, Hirokazu, Inoue, Gen, Miyagi, Masayuki, Saito, Wataru, Nakano, Atsushi, Sakai, Daisuke, Nukaga, Tadashi, Ikegami, Shota, Shimizu, Masayuki, Futatsugi, Toshimasa, Ohtori, Seiji, Furuya, Takeo, Orita, Sumihisa, Imagama, Shiro, Ando, Kei, Kobayashi, Kazuyoshi, Kiyasu, Katsuhito, Murakami, Hideki, Yoshioka, Katsuhito, Seki, Shoji, Hongo, Michio, Kakutani, Kenichiro, Yurube, Takashi, Aoki, Yasuchika, Oshima, Masashi, Takahata, Masahiko, Iwata, Akira, Endo, Hirooki, Abe, Tetsuya, Tsukanishi, Toshinori, Nakanishi, Kazuyoshi, Watanabe, Kota, Hikata, Tomohiro, Suzuki, Satoshi, Isogai, Norihiro, Okada, Eijiro, Funao, Haruki, Ueda, Seiji, Shiono, Yuta, Nojiri, Kenya, Hosogane, Naobumi, Ishii, Ken   +68 more
openaire   +1 more source

Factors affecting mortality in late stage Parkinson’s Disease [PDF]

, 2019
To determine the effect of dysphagia and hospital admissions on mortality in late stage Parkinson’s ...
Dempsey, S., Gray, William Keith, Hand, Annette, McDonald, L., Sayers, I., Walker, Richard   +5 more
core   +1 more source

On the analysis of EEG power, frequency and asymmetry in Parkinson's disease during emotion processing [PDF]

, 2014
Objective: While Parkinson’s disease (PD) has traditionally been described as a movement disorder, there is growing evidence of disruption in emotion information processing associated with the disease.
Ibrahim, Norlinah Mohamed, Mesquita, Edgar, Mohamad, Khairiyah, Murugappan, Murugappan, Omar, Mohd Iqbal, Palaniappan, Ramaswamy, Satiyan, Marimuthu, Sundaraj, Kenneth, Yuvaraj, Rajamanickam   +8 more
core   +2 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Essential Tremor and Parkinson’s Disease: Exploring the Relationship

Tremor and Other Hyperkinetic Movements, 2019
Background: There is longstanding controversy surrounding the possible link between essential tremor (ET) and Parkinson’s disease (PD). Inconsistent and unreliable diagnostic criteria may in part account for some of the difficulties in defining the ...
Arjun Tarakad, Joseph Jankovic
doaj   +1 more source

MOESM1 of Brain mediators of systemic oxidative stress on perceptual impairments in Parkinsonâ s disease

, 2015
Additional file 1. Detail T1-weighted structural MRI image processing procedures.
Lin, Wei-Che, Chou, Kun-Hsien, Lee, Pei-Lin, Huang, Yung-Cheng, Tsai, Nai-Wen, Chen, Hsiu-Ling, Cheng, Kuei-Yueh, Wang, Hung-Chen, Lin, Tsu-Kung, Li, Shau-Hsuan, Chen, Meng-Hsiang, Lu, Cheng-Hsien, Lin, Ching-Po   +12 more
openaire   +1 more source