Results 141 to 150 of about 9,618,511 (343)

Additional file 1: of Parkinsonâ s disease in China: a forty-year growing track of bedside work

, 2019
Table S1. Epidemiology of PD in China. Table S2. Status of Clinical Trials. Data S3. Meta analysis of genetic variants for Parkinsonâ s disease in Chinese population. (DOCX 38298 kb)
Li, Gen, Ma, Jianfang, Cui, Shishuang, He, Yixi, Xiao, Qin, Liu, Jun, Chen, Shengdi   +6 more
openaire   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results

Movement Disorders, 2008
C. Goetz, B. Tilley, S. Shaftman, G. Stebbins, S. Fahn, P. Martínez-Martín, W. Poewe, C. Sampaio, M. Stern, R. Dodel, B. Dubois, R. Holloway, J. Jankovic, J. Kulisevsky, A. Lang, A. Lees, S. Leurgans, P. LeWitt, D. Nyenhuis, C. Olanow, O. Rascol, A. Schrag, J. Teresi, J. J. van Hilten, Nancy Lapelle   +24 more
semanticscholar   +1 more source

A Smartphone Application as an Exploratory Endpoint in a Phase 3 Parkinson’s Disease Clinical Trial: A Pilot Study [PDF]

, 2022
Alex Page, Norman C.W. Yung, Peggy Auinger, Charles S. Venuto, Alistair M. Glidden, Eric A. Macklin, Larsson Omberg, Michael A. Schwarzschild, E. Ray Dorsey   +8 more
openalex   +1 more source

Additional file 1 of Altered gut microbiota and inflammatory cytokine responses in patients with Parkinsonâ s disease

, 2019
: Supplementary methods. (DOCX 21Â kb)
Chin-Hsien Lin, Chieh-Chang Chen, Chiang, Han-Lin, Jyh-Ming Liou, Chih-Min Chang, Tzu-Pin Lu, Chuang, Eric, Tai, Yi-Cheng, Chieh Cheng, Han-Yi Lin, Ming-Shiang Wu   +10 more
openaire   +1 more source

Boron‐Doped Nano‐Crystalline Coated Carbon Fibers for Phasic Dopamine Sensing

Advanced Healthcare Materials, EarlyView.
This uniform coating presents a mix of graphitic and diamond‐like carbon to create a mechanically and electrically robust alternative for the electrochemical detection of dopamine. The electrodes in this work possess the equivalent sensitivity to the state‐of‐the‐art FSCV dopamine detecting electrodes, whilst demonstrating an ability to withstand ...
Simon J. Higham, Juan M. Rojas Cabrera, Youngjong Kwak, Lydia Hong, Andre Chambers, Athavan Nadarajah, Sorel E. De Leon, Young Jun Jung, Negin Jalilinejad, Charles Blaha, Dong Pyo Jang, Yoonbae Oh, Kendall Lee, Alastair Stacey, Shaun L. Cloherty, Michael R. Ibbotson, David J. Garrett, Steven Prawer, Hojin Shin, Wei Tong   +19 more
wiley   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Additional file 1: of Recent advances in rehabilitation for Parkinsonâ s Disease with Exergames: A Systematic Review

, 2019
Table S1. Overview of the selected RCTs and Pilot Studies (PDF 276 kb)
Garcia-Agundez, Augusto, Ann-Kristin Folkerts, Konrad, Robert, Caserman, Polona, Tregel, Thomas, Goosses, Mareike, GĂśbel, Stefan, Kalbe, Elke   +7 more
openaire   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Nature Neuroscience, 2000
R. Betarbet, T. Sherer, G. Mackenzie, M. Garcia-Osuna, A. Panov, J. Greenamyre   +5 more
semanticscholar   +1 more source