Results 161 to 170 of about 457,449 (311)

Additional file 1: Figure S1. of The RAB39B p.G192R mutation causes X-linked dominant Parkinsonâ s disease

, 2015
Pedigrees with variants of unknown significance. Pedigrees in which the RAB39B (A) c.428C>G (p.A143G) and (B) c.624_626delGAG (p.R209del) variants were observed. Individuals affected with Parkinsonâ s disease are represented with black symbols, unaffected individuals with open symbols.
Mata, Ignacio, Yongwoo Jang, Chun-Hyung Kim, Hanna, David, Dorschner, Michael, Samii, Ali, Pinky Agarwal, Roberts, John, Klepitskaya, Olga, Shprecher, David, Chung, Kathryn, Factor, Stewart, Espay, Alberto, Revilla, Fredy, Higgins, Donald, Litvan, Irene, Leverenz, James, Yearout, Dora, Inca-Martinez, Miguel, Martinez, Erica, Thompson, Tiffany, Cholerton, Brenna, Shu-Ching Hu, Edwards, Karen, Kim, Kwang-Soo, Zabetian, Cyrus   +25 more
openaire   +1 more source

PolyGraph – Flexible, Biocompatible & Electrically Optimized Graphene‐Polymer Composites for Next‐Generation Neural Interfaces

Advanced Healthcare Materials, EarlyView.
PolyGraph, a flexible graphene‐polycaprolactone nanocomposite, unites conductivity, biocompatibility, and processability for next‐generation neural interfaces. Fabricated into microneedle arrays with ultra‐flexible backings, PolyGraph enables bidirectional neuronal recording and stimulation in brain tissue, advancing brain‐computer interface (BCI) and ...
Jack Maughan, Ian Woods, Cian O'Connor, Pablo Quintana‐Sarti, Eoin Caffrey, Jose M. Munuera, Tian Carey, Adrian Dervan, Alejandro López Valdés, Omar Mamad, Maeve A. Caldwell, Fergal J. O'Brien, Jonathan N. Coleman   +12 more
wiley   +1 more source

Multimodal oculomotor assessment reveals prodromal markers of Parkinson’s disease in non-manifesting LRRK2 G2019S mutation carriers

npj Parkinson's Disease
Oculomotor behaviour changes in patients with Parkinson’s disease (PD) are a promising source of prodromal disease markers. Capitalizing on this phenomenon to facilitate early diagnosis requires oculomotor assessment in prodromal cohorts.
Heidi C. Riek, Naomi P. Visanji, Isabell C. Pitigoi, Daniel G. Di Luca, Laura Armengou-Garcia, Nazish Ahmed, Julia E. Perkins, Donald C. Brien, Jeff Huang, Brian C. Coe, Jana Huang, Taneera Ghate, Anthony E. Lang, Connie Marras, Douglas P. Munoz   +14 more
doaj   +1 more source

Additional file 1: of Status of the Parkinsonâ s disease gene family expression in non-small-cell lung cancer

, 2015
Results of t -test for gender and histology.
Liu, Quan, Zheng, Hong, Deng, Xu, Zhou, Dong, Dai, Ji   +4 more
openaire   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

Additional file 2: of Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinsonâ s disease

, 2015
Supplementary online material. (DOCX 119 kb)
Tamburrino, Anna, Churchill, Madeline, Oi Wan, Colino-Sanguino, Yolanda, Ippolito, Rossana, Bergstrand, Sofie, Wolf, Daniel, Niculin Herz, Sconce, Michelle, BjĂśrklund, Anders, Meshul, Charles, Decressac, Mickael   +11 more
openaire   +1 more source

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

Additional file 1: of Evaluation of rotigotine transdermal patch for the treatment of apathy and motor symptoms in Parkinsonâ s disease

, 2016
Institutional Review Boards or Independent Ethics Committees of participating sites in the PD0005 study. (PDF 220 kb)
Hauser, Robert, Jaroslaw Slawek, Barone, Paolo, Dohin, Elisabeth, Surmann, Erwin, Asgharnejad, Mahnaz, Bauer, Lars   +6 more
openaire   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Additional file 2: of Identification of plasma microRNA expression changes in multiple system atrophy and Parkinsonâ s disease

, 2019
Table S2. Top 50 predicted target genes for each miRNA using miRmap. (DOCX 22 kb)
Uwatoko, Hisashi, Hama, Yuka, Iwata, Ikuko, Shirai, Shinichi, Matsushima, Masaaki, Yabe, Ichiro, Utsumi, Jun, Sasaki, Hidenao   +7 more
openaire   +1 more source