Results 171 to 180 of about 263,626 (317)

Additional file 2: of Identification of plasma microRNA expression changes in multiple system atrophy and Parkinsonâ s disease

, 2019
Table S2. Top 50 predicted target genes for each miRNA using miRmap. (DOCX 22 kb)
Uwatoko, Hisashi, Hama, Yuka, Iwata, Ikuko, Shirai, Shinichi, Matsushima, Masaaki, Yabe, Ichiro, Utsumi, Jun, Sasaki, Hidenao   +7 more
openaire   +1 more source

Pharmacotherapy of motor symptoms in early and mid-stage Parkinson’s disease: guideline “Parkinson’s disease” of the German Society of Neurology

Background and objective There are multiple pharmacological treatment options for motor symptoms of Parkinson’s disease (PD). These comprise multiple drug classes which are approved for the condition, including levodopa, dopamine agonists, COMT ...
Becktepe, Jos, Höglinger, Günter U., German Parkinson’s Guidelines Group, Deuschl, Günther, Classen, Joseph, Hopfner, Franziska, Löhle, Matthias, Ebersbach, Georg, Pötter-Nerger, Monika, Lingor, Paul, Maaß, Sylvia, Höllerhage, Matthias   +11 more
core   +1 more source

Developing a Functional Polyelectrolyte Hybrid Layer Scaffold Coating and Evaluation of Its Performance for Interaction With Neural Cells

Advanced Materials Interfaces, EarlyView.
Polyelectrolyte scaffold coatings modified with Cu and Fe3O4 nanoparticles regulate neural stem cell behavior in vitro. Increased Fe3O4 content enhances mitochondrial activity and neuronal differentiation, whereas higher Cu levels reduce cell viability.
Anna Grzeczkowicz, Agata Lipko, Angelika Kwiatkowska, Marcin Strawski, Monika Drabik, Ludomira H. Granicka   +5 more
wiley   +1 more source

Additional file 1: of Nicotine promotes neuron survival and partially protects from Parkinsonâ s disease by suppressing SIRT6

, 2018
Figure S1. Human brain tissue analysis by SDS-PAGE. Figure S2. Cigarette smoke extract apparatus, nicotine blots, and proteasome activity. Figure S3. Transgenic mice and brain expression. Figure S4. SIRT6 OX neurons secrete more TNFÎą than WT. Figure S5. Primary neuronal culture composition. Figure S6.
Nicholatos, Justin, Francisco, Adam, Bender, Carolyn, Yeh, Tiffany, Lugay, Fraz, Salazar, Jairo, Glorioso, Christin, Libert, Sergiy   +7 more
openaire   +1 more source

RESTORATION OF MOTOR AND NON-MOTOR FUNCTIONS BY NEUROTROPHIC FACTORS IN NONHUMAN PRIMATES WITH DOPAMINE DEPLETION [PDF]

, 2013
Parkinson’s disease (PD) is a progressive debilitating neurodegenerative disorder characterized by resting tremor, rigidity, bradykinesia and postural instability. As the disease progresses there is a loss of dopamine (DA) neurons in the substantia nigra
Subramanian, Krishna
core  

Iron deficiency in parkinsonism : region-specific iron dysregulation in Parkinson's disease and multiple system atrophy [PDF]

Alpha synuclein pathology is widespread and found in diverse cell types in multiple system atrophy (MSA) as compared to Parkinson's disease (PD). The reason for this differential distribution is unknown.
Visanji, Naomi P., Finnegan, Mary E., Collingwood, Joanna F., Hazrati, Lili-Naz, Tandon, Anurag, House, Emily   +5 more
core   +1 more source

Minimally Invasive Delivery of Optical Nanosensors Using Injectable Hydrogels

Advanced Materials Interfaces, EarlyView.
Injectable peptide hydrogels offer a minimally invasive delivery platform for single‐walled carbon nanotube (SWCNT)‐based near‐infrared fluorescent sensors, enabling real‐time measurement of drug concentrations. Encapsulated SWCNTs show a dose‐dependent fluorescence response across physiologically relevant concentrations and retain their fluorescence ...
Shirel Kleiner, Gili Bisker
wiley   +1 more source

Additional file 4: of Identification of plasma microRNA expression changes in multiple system atrophy and Parkinsonâ s disease

, 2019
Table S4. Top 15 statistically significant GO processes relevant to the top 50 predicted target genes of hsa-miR-24-3p. (DOCX 18 kb)
Uwatoko, Hisashi, Hama, Yuka, Iwata, Ikuko, Shirai, Shinichi, Matsushima, Masaaki, Yabe, Ichiro, Utsumi, Jun, Sasaki, Hidenao   +7 more
openaire   +1 more source

Cognitive deficits and structural brain changes associated with dementia and visual hallucinations in Parkinson's disease [PDF]

, 2006
[eng] Cognitive impairment of different degrees and hallucinations are common complications of chronic Parkinson's disease (PD). The pathogenesis, pathophysiology, and relationship between cognitive deficits and presence of hallucinations are not fully ...
Ramírez Ruiz, Blanca
core  

Remote Control of Hand Actuators via Glove Sensors for Medical Care Applications

Advanced Robotics Research, EarlyView.
This study presents a novel textile‐based sensory glove–actuator system for remote medical care, explored through finite element simulations. By integrating capacitive sensors, pneumatic actuators, and machine learning, the system models real‐time hand movement control.
Bahman Taherkhani, Mahdi Bodaghi
wiley   +1 more source