Results 21 to 30 of about 9,306,982 (363)

Motor function in Parkinson's disease and supranuclear palsy: simultaneous factor analysis of a clinical scale in several populations

BMC Medical Research Methodology, 2006
BackgroundIn order to better understand the similarities and differences in the motor behaviour of different groups of patients, their scores on the Motor Examination section of the Unified Parkinson's Disease Rating Scale (UPDRS) were analysed ...
P. Kroonenberg, Frans J Oort, G. Stebbins, Sue E. Leurgans, Esther Cubo, C. Goetz   +5 more
semanticscholar   +1 more source

MOESM1 of White matter damage and systemic inflammation in Parkinsonâ s disease

, 2017
Additional file 1: Supplementary methods of DTI data preprocessing and analysis.
Pi-Ling Chiang, Hsiu-Ling Chen, Cheng-Hsien Lu, Pei-Chin Chen, Meng-Hsiang Chen, I.-Hsiao Yang, Nai-Wen Tsai, Wei-Che Lin   +7 more
openaire   +1 more source

Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease.

New England Journal of Medicine, 2003
BACKGROUND Although the short-term benefits of bilateral stimulation of the subthalamic nucleus in patients with advanced Parkinson's disease have been well documented, the long-term outcomes of the procedure are unknown.
P. Krack, A. Batir, N. Van Blercom, S. Chabardès, V. Fraix, C. Ardouin, A. Koudsié, P. Limousin, A. Benazzouz, J. Lebas, A. Benabid, P. Pollak   +11 more
semanticscholar   +1 more source

MOESM2 of White matter damage and systemic inflammation in Parkinsonâ s disease

, 2017
Additional file 2: Partial correlation between DTI indices and clinical disease severity.
Pi-Ling Chiang, Hsiu-Ling Chen, Cheng-Hsien Lu, Pei-Chin Chen, Meng-Hsiang Chen, I.-Hsiao Yang, Nai-Wen Tsai, Wei-Che Lin   +7 more
openaire   +1 more source

Morphological changes of glutamatergic synapses in animal models of Parkinson’s disease

Frontiers in Neuroanatomy, 2015
The striatum and the subthalamic nucleus are the main entry doors for extrinsic inputs to reach the basal ganglia circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei.
Rosa M Villalba, Rosa M Villalba, Abraham eMathai, Abraham eMathai, Yoland eSmith, Yoland eSmith, Yoland eSmith   +6 more
doaj   +1 more source

Essential Tremor and Parkinson’s Disease: Exploring the Relationship

Tremor and Other Hyperkinetic Movements, 2019
Background: There is longstanding controversy surrounding the possible link between essential tremor (ET) and Parkinson’s disease (PD). Inconsistent and unreliable diagnostic criteria may in part account for some of the difficulties in defining the ...
Arjun Tarakad, Joseph Jankovic
doaj   +1 more source

MOESM4 of A randomized controlled efficacy study of the Medido medication dispenser in Parkinsonâ s disease

, 2019
Additional file 4. Table with secondary outcomes of PDQ-carer.
K. Hannink, L. Brake, N.G.M. Oonk, A.A. Wertenbroek, M. Piek, L. Vree-Egberts, M.J. Faber, J. Palen, L.D. Dorresteijn   +8 more
openaire   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

npj Parkinson's Disease
Understanding medium spiny neuron (MSN) physiology is essential to understand motor impairments in Parkinson’s disease (PD) given the architecture of the basal ganglia.
Quyen B. Do, Humaira Noor, Ricardo Marquez-Gomez, Kaitlyn M. L. Cramb, Bryan Ng, Ajantha Abbey, Naroa Ibarra-Aizpurua, Maria Claudia Caiazza, Parnaz Sharifi, Charmaine Lang, Dayne Beccano-Kelly, Jimena Baleriola, Nora Bengoa-Vergniory, Richard Wade-Martins   +13 more
doaj   +1 more source

Live Imaging of Axonal Transport in the Motor Neurons of Drosophila Larvae

Bio-Protocol, 2017
Axonal transport, which is composed of microtubules, motor proteins and a variety of types of cargo, is a prominent feature of neurons. Monitoring these molecular dynamics is important to understand the biological processes of neurons as well as ...
Tsuyoshi Inoshita, Nobutaka Hattori, Yuzuru Imai   +2 more
doaj   +1 more source