Results 11 to 20 of about 213,160 (266)

Targeting Aggrephagy for the Treatment of Alzheimer’s Disease

Cells, 2020
Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases in older individuals with specific neuropsychiatric symptoms. It is a proteinopathy, pathologically characterized by the presence of misfolded protein (Aβ and Tau ...
Sandeep Malampati, Ju-Xian Song, Benjamin Chun-Kit Tong, Anusha Nalluri, Chuan-Bin Yang, Ziying Wang, Sravan Gopalkrishnashetty Sreenivasmurthy, Zhou Zhu, Jia Liu, Chengfu Su, Senthilkumar Krishnamoorthi, Ashok Iyaswamy, King-Ho Cheung, Jia-Hong Lu, Min Li   +14 more
doaj   +1 more source

Clinical Characteristics of Involuntary Movement in Hospitalized Patients [PDF]

Journal of Movement Disorders, 2019
Objective Neurological symptoms in hospitalized patients are not rare, and neurological consultation for movement disorders is especially important in evaluating or managing those with various movement disorders.
Kyum-Yil Kwon, Hye Mi Lee, Seon-Min Lee, Seong-Beom Koh   +3 more
doaj   +1 more source

Deep learning algorithm reveals two prognostic subtypes in patients with gliomas

BMC Bioinformatics, 2022
Background Gliomas are highly complex and heterogeneous tumors, rendering prognosis prediction challenging. The advent of deep learning algorithms and the accessibility of multi-omic data represent a new approach for the identification of survival ...
Jing Tian, Mingzhen Zhu, Zijing Ren, Qiang Zhao, Puqing Wang, Colin K. He, Min Zhang, Xiaochun Peng, Beilei Wu, Rujia Feng, Minglong Fu   +10 more
doaj   +1 more source

Palliative care for Parkinson’s disease: suggestions from a council of patient and carepartners

npj Parkinson's Disease, 2017
In 2015, the Parkinson’s Disease Foundation sponsored the first international meeting on Palliative Care and Parkinson’s disease and the Patient Centered Outcomes Research Institute funded the first comparative effectiveness trial of palliative care for ...
Kirk Hall, Malenna Sumrall, Gil Thelen, Benzi M. Kluger, on behalf of the 2015 Parkinson’s Disease Foundation sponsored “Palliative Care and Parkinson’s Disease” Patient Advisory Council   +4 more
doaj   +1 more source

How Cognition and Motivation “Freeze” the Motor Behavior in Parkinson’s Disease

Frontiers in Neuroscience, 2019
ObjectiveFreezing of gait (FoG) is a debilitating problem in patients with PD. The multifactorial pathogenesis of FoG remains poorly understood. We aimed to find which factors are most strongly associated with the occurrence of FoG.MethodsThree hundred ...
Paola Ortelli, Davide Ferrazzoli, Veronica Cian, Veronica Cian, Marianna Zarucchi, Grazia Palamara, Alessandro Giobbia, Giuseppe Frazzitta, Roberto Maestri, Margherita Canesi   +9 more
doaj   +1 more source

Drug Repurposing for Parkinson’s Disease: The International Linked Clinical Trials experience

Frontiers in Neuroscience, 2021
The international Linked Clinical Trials (iLCT) program for Parkinson’s to date represents one of the most comprehensive drug repurposing programs focused on one disease.
Simon R. W. Stott, Richard K. Wyse, Patrik Brundin   +2 more
doaj   +1 more source

Additional file 2: of Responsiveness of the short-form health survey and the Parkinsonâ s disease questionnaire in patients with Parkinsonâ s disease

, 2017
Internal responsiveness of HRQoL in the stable patient group. (DOCX 20 kb)
Tu, Xiao-Jing, Wen-Juh Hwang, Shih-Pin Hsu, Hui-Ing Ma   +3 more
openaire   +1 more source

MOESM2 of White matter damage and systemic inflammation in Parkinsonâ s disease

, 2017
Additional file 2: Partial correlation between DTI indices and clinical disease severity.
Chiang, Pi-Ling, Chen, Hsiu-Ling, Lu, Cheng-Hsien, Chen, Pei-Chin, Chen, Meng-Hsiang, Yang, I.-Hsiao, Tsai, Nai-Wen, Lin, Wei-Che   +7 more
openaire   +1 more source

MOESM1 of White matter damage and systemic inflammation in Parkinsonâ s disease

, 2017
Additional file 1: Supplementary methods of DTI data preprocessing and analysis.
Chiang, Pi-Ling, Chen, Hsiu-Ling, Lu, Cheng-Hsien, Chen, Pei-Chin, Chen, Meng-Hsiang, Yang, I.-Hsiao, Tsai, Nai-Wen, Lin, Wei-Che   +7 more
openaire   +1 more source

Additional file 1: of Cerebellar involvement in Parkinsonâ s disease resting tremor

, 2016
Summary Analysis Data. (DOCX 13 kb)
Lefaivre, Shannon, Brown, Matt, Almeida, Quincy   +2 more
openaire   +1 more source