Results 11 to 20 of about 5,079,684 (260)

Between Truth and Hope : On Parkinson's Disease, Neurotransplantation and the Production of the 'Self'. [PDF]

, 2005
In this article, we argue that contemporary biomedicine is shaped by two, seemingly incommensurable, organizational logics, the ‘regime of truth’ and the ‘regime of hope’.
Palladino, Paolo, Moreira, Tiago
core   +5 more sources

Applications of the European Parkinson’s Disease Association sponsored Parkinson’s Disease Composite Scale (PDCS) [PDF]

, 2019
This study was addressed to determine the presence of Parkinson disease (PD) manifestations, their distribution according to motor subtypes, and the relationships with health-related quality of life (QoL) using the recently validated European Parkinson's
Rodriguez-Blazquez, Carmen, Stocchi, Fabrizio, Martinez-Martin, Pablo, Chaudhuri, Kallol Ray, PDCS European Study Group, Balestrino, Roberta, Hurtado-Gonzalez, Carlos Alberto, Rodriguez Blazquez, Carmen, Giada Radicati, Fabiana, Hurtado González, Carlos Alberto, Radicati, Fabiana Giada, Chaudhuri, Ray, The PDCS European Study Group, Chaudhuri, K. Ray, Vuletić, Vladimira, Martinez Martin, Pablo, Chaudhuri, K Ray   +16 more
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Oxidative stress in genetic mouse models of Parkinson's disease [PDF]

, 2012
There is extensive evidence in Parkinson’s disease of a link between oxidative stress and some of the monogenically inherited Parkinson’s disease-associated genes.
Bentea, Eduard, Michotte, Yvette, Varcin, Mustafa, Sarre, Sophie   +3 more
core   +1 more source

Retraining function in people with Parkinson’s disease using the Microsoft kinect: game design and pilot testing [PDF]

, 2014
Background Computer based gaming systems, such as the Microsoft Kinect (Kinect), can facilitate complex task practice, enhance sensory feedback and action observation in novel, relevant and motivating modes of exercise which can be difficult to ...
Madeline Balaam, Dadirayi Mhiripiri, Scholfield, Guy, Galna, Brook, Jackson, Dan, Brook Galna, Balaam, M., Gillian Barry, Jackson, Daniel, Galna, B., Roisin McNaney, Rochester, Lynn, McNaney, Roisin, Schofield, G., Lynn Rochester, Dan Jackson, Schofield, Guy, Webster, M., Mhiripiri, Dadirayi, Mary Webster, McNaney, R., Jackson, D., Balaam, Madeline,, Mhiripiri, D., Patrick Olivier, Webster, Mary, Balaam, Madeline, Olivier, P., Rochester, L., Olivier, Patrick, Barry, G., Barry, Gillian, Guy Schofield   +32 more
core   +1 more source

A novel biomechanical analysis of gait changes in the MPTP mouse model of Parkinson’s disease [PDF]

, 2015
Parkinson's disease (PD) is an age-associated neurodegenerative disorder hallmarked by a loss of mesencephalic dopaminergic neurons. Accurate recapitulation of the PD movement phenotype in animal models of the disease is critical for understanding ...
Geldenhuys, Werner, Pienaar, Ilse, Young, Jesse, Dean E. Dluzen, Werner J. Geldenhuys, Tamara L. Guseman, Ilse S. Pienaar, Jesse W. Young, Dluzen, Dean, Guseman, Tamara   +9 more
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Palliative care for Parkinson’s disease: suggestions from a council of patient and carepartners

npj Parkinson's Disease, 2017
In 2015, the Parkinson’s Disease Foundation sponsored the first international meeting on Palliative Care and Parkinson’s disease and the Patient Centered Outcomes Research Institute funded the first comparative effectiveness trial of palliative care for ...
Kirk Hall, Malenna Sumrall, Gil Thelen, Benzi M. Kluger, on behalf of the 2015 Parkinson’s Disease Foundation sponsored “Palliative Care and Parkinson’s Disease” Patient Advisory Council   +4 more
doaj   +1 more source

Clinical Characteristics of Involuntary Movement in Hospitalized Patients [PDF]

Journal of Movement Disorders, 2019
Objective Neurological symptoms in hospitalized patients are not rare, and neurological consultation for movement disorders is especially important in evaluating or managing those with various movement disorders.
Kyum-Yil Kwon, Hye Mi Lee, Seon-Min Lee, Seong-Beom Koh   +3 more
doaj   +1 more source

Targeting Aggrephagy for the Treatment of Alzheimer’s Disease

Cells, 2020
Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases in older individuals with specific neuropsychiatric symptoms. It is a proteinopathy, pathologically characterized by the presence of misfolded protein (Aβ and Tau ...
Sandeep Malampati, Ju-Xian Song, Benjamin Chun-Kit Tong, Anusha Nalluri, Chuan-Bin Yang, Ziying Wang, Sravan Gopalkrishnashetty Sreenivasmurthy, Zhou Zhu, Jia Liu, Chengfu Su, Senthilkumar Krishnamoorthi, Ashok Iyaswamy, King-Ho Cheung, Jia-Hong Lu, Min Li   +14 more
doaj   +1 more source

Deep learning algorithm reveals two prognostic subtypes in patients with gliomas

BMC Bioinformatics, 2022
Background Gliomas are highly complex and heterogeneous tumors, rendering prognosis prediction challenging. The advent of deep learning algorithms and the accessibility of multi-omic data represent a new approach for the identification of survival ...
Jing Tian, Mingzhen Zhu, Zijing Ren, Qiang Zhao, Puqing Wang, Colin K. He, Min Zhang, Xiaochun Peng, Beilei Wu, Rujia Feng, Minglong Fu   +10 more
doaj   +1 more source

Drug Repurposing for Parkinson’s Disease: The International Linked Clinical Trials experience

Frontiers in Neuroscience, 2021
The international Linked Clinical Trials (iLCT) program for Parkinson’s to date represents one of the most comprehensive drug repurposing programs focused on one disease.
Simon R. W. Stott, Richard K. Wyse, Patrik Brundin   +2 more
doaj   +1 more source