Drug Repurposing for Parkinson’s Disease: The International Linked Clinical Trials experience
The international Linked Clinical Trials (iLCT) program for Parkinson’s to date represents one of the most comprehensive drug repurposing programs focused on one disease.
Simon R. W. Stott +2 more
doaj +1 more source
Parkinson's disease - psychological determinants of quality of life [PDF]
There are many studies, which are focused on measurement the quality of life (QoL) of patients with Parkinson’s disease (PD), but studies about psychological factors associated with QoL in those patients are scarce.
Dubayova, Tatiana,, Dubayova, Tatiana
core +1 more source
Measuring anxiety in Lewy Body Disease – Which scale to choose?
Background: Anxiety is among the most prevalent mood disorders in Lewy Body Disease (LBD) (i.e., Parkinson’s disease (PD), Dementia with Lewy bodies DLB), and those at-risk for developing LBD (e.g. isolated REM Sleep Behaviour Disorder (iRBD)).
Isabel Paniak +2 more
doaj +1 more source
Internal responsiveness of HRQoL in the stable patient group. (DOCX 20 kb)
Tu, Xiao-Jing +3 more
openaire +1 more source
Auditory observation of stepping actions can cue both spatial and temporal components of gait in Parkinson's disease patients [PDF]
Objectives: A common behavioural symptom of Parkinson’s disease (PD) is reduced step length (SL). Whilst sensory cueing strategies can be effective in increasing SL and reducing gait variability, current cueing strategies conveying spatial or temporal ...
Young, William R. +6 more
core +1 more source
MOESM2 of White matter damage and systemic inflammation in Parkinsonâ s disease
Additional file 2: Partial correlation between DTI indices and clinical disease severity.
Chiang, Pi-Ling +7 more
openaire +1 more source
MOESM1 of White matter damage and systemic inflammation in Parkinsonâ s disease
Additional file 1: Supplementary methods of DTI data preprocessing and analysis.
Chiang, Pi-Ling +7 more
openaire +1 more source
Morphological changes of glutamatergic synapses in animal models of Parkinson’s disease
The striatum and the subthalamic nucleus are the main entry doors for extrinsic inputs to reach the basal ganglia circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei.
Rosa M Villalba +6 more
doaj +1 more source
Association between changes in visual evoked magnetic fields and non-motor features in Parkinson’s disease [PDF]
2017-05Visual dysfunction can be caused by several abnormalities, including dysfunctions in the visual cortex and retina. Our aim was to investigate changes in visual evoked brain responses in the primary visual cortex associated with Parkinson’s disease
Uemura, Jun-ichi +5 more
core +1 more source
Additional file 1: of Cerebellar involvement in Parkinsonâ s disease resting tremor
Summary Analysis Data. (DOCX 13 kb)
Lefaivre, Shannon +2 more
openaire +1 more source

