Results 81 to 90 of about 236,137 (343)
Early Language Impairment as an Integral Part of the Cognitive Phenotype in Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Huntington's disease (HD) speech/language disorders have typically been attributed to motor and executive impairment due to striatal dysfunction. In‐depth study of linguistic skills and the role of extrastriatal structures in HD is scarce.
Arnau Puig‐Davi +13 more
wiley +1 more source
Increasing the Discovery Power and Confidence Levels of Disease Association Studies: A Survey [PDF]
arXiv, 2017 The majority of common diseases are influenced by multiple genetic and environmental factors such as Cancer. Even though uncovering the main causes of disease is deemed difficult due to the complexity of gene-gene and gene-environment interactions, major research efforts aim at identifying disease risk factors, especially genetic ones.
arxiv
Additional file 1: of Meta-analysis of risk factors for Parkinsonâ s disease dementia
, 2016 Details of studies included in the meta-analysis. This file included details of all studies included in this meta-analysis, categorized by risk factors. Details including first author, year of publication, country, study design, number of participants and NOS scores. (DOCX 119 kb)
Yaqian Xu, Yang, Jing, Huifang Shang
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra +17 more
wiley +1 more source
Pilot and Feasibility Studies, 2019 Background One of the greatest barriers found by physical therapy treating individuals with Parkinson’s disease (PD) is the adherence to treatment, associated with the lack of motivation to remain active.
Helena de Oliveira Braga +7 more
doaj +1 more source
Translational Neurodegeneration, 2020 Background The efficacy and safety of opicapone, a once-daily catechol-O-methyltransferase inhibitor, have been established in two large randomized, placebo-controlled, multinational pivotal trials.
Heinz Reichmann +5 more
doaj +1 more source
The development of nations conditions the disease space [PDF]
arXiv, 2019 Using the economic complexity methodology on data for disease prevalence in 195 countries during the period of 1990-2016, we propose two new metrics for quantifying the relatedness between diseases, or the `disease space' of countries. With these metrics, we analyze the geography of diseases and empirically investigate the effect of economic ...
arxiv
, 2019 Additional file 2. Table with secondary outcomes of EQ5D-5L, VAS, NMS-Quest.
K. Hannink +8 more
openaire +1 more source
Immunogenicity Associated with Botulinum Toxin Treatment
Toxins, 2019 Botulinum toxin (BoNT) has been used for the treatment of a variety of neurologic, medical and cosmetic conditions. Two serotypes, type A (BoNT-A) and type B (BoNT-B), are currently in clinical use. While considered safe and effective, their use has been
Steven Bellows, Joseph Jankovic
doaj +1 more source
Additional file 10: of Blood transcriptomics of drug-naĂŻve sporadic Parkinsonâ s disease patients
, 2015 List of common genes between A9 DA neurons of the SN in the mouse and differentially expressed transcripts in the blood of PD patients according to SAM (a) and PUMA (b). (PDF 3122 kb)
Calligaris, Raffaella +17 more
openaire +1 more source