Recent Advances in Understanding and Managing Tourette Syndrome [version 1; referees: 3 approved]
Tourette syndrome (TS) is a neurologic and behavioral disorder consisting of motor and phonic tics with onset in childhood or adolescence. The severity of tics can range from barely perceptible to severely impairing due to social embarrassment ...
Mary Ann Thenganatt, Joseph Jankovic
doaj +1 more source
Background The efficacy and safety of opicapone, a once-daily catechol-O-methyltransferase inhibitor, have been established in two large randomized, placebo-controlled, multinational pivotal trials.
Heinz Reichmann +5 more
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Additional file 1: of Meta-analysis of risk factors for Parkinsonâ s disease dementia
Details of studies included in the meta-analysis. This file included details of all studies included in this meta-analysis, categorized by risk factors. Details including first author, year of publication, country, study design, number of participants and NOS scores. (DOCX 119 kb)
Yaqian Xu, Yang, Jing, Huifang Shang
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Functional magnetic stimulation in constipation associated with Parkinson’s disease
The aims of this study were: (i) to investigate the effect of functional magnetic stimulation on total colonic transit time in patients with Parkinson's disease; (ii) to compare the changes in dynamic recto-anal behaviour during filling and defaecation in response to this regimen; and (iii) to study the carry-over effects with a 3-month follow-up.A ...
Cheng-Ming, Chiu +5 more
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Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel +5 more
wiley +1 more source
Additional file 4: of Blood transcriptomics of drug-naĂŻve sporadic Parkinsonâ s disease patients
Square of the Mahalanobis distance calculated for each sample from both control and pathological class models. (PDF 3122 kb)
Calligaris, Raffaella +17 more
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Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Update on treatments for nonmotor symptoms of Parkinson's disease—an evidence‐based medicine review
To update evidence‐based medicine recommendations for treating nonmotor symptoms in Parkinson's disease (PD).
K. Seppi +14 more
semanticscholar +1 more source
Neuromuscular Electrical Stimulation for Sialorrhea in an Elderly Woman With Parkinson’s Disease [PDF]
Yuki Kojima, Yutaka Sakaguchi
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MOESM2 of Prevalence and incidence of Parkinsonâ s disease and drug-induced parkinsonism in Korea
Additional file 2: Figure S1. Sensitivity analysis. Incidence of drug-induced parkinsonism in Korea.
Sola Han +5 more
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