Results 1 to 10 of about 125,678 (274)

APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson's Disease

Frontiers in Neurology, 2021
Introduction: Cognitive decline and dementia are common and debilitating non-motor phenotypic features of Parkinson's disease with a variable severity and time of onset.
Jon-Anders Tunold, Jon-Anders Tunold, Hanneke Geut, J. M. Annemieke Rozemuller, Sandra Pilar Henriksen, Mathias Toft, Mathias Toft, Wilma D. J. van de Berg, Lasse Pihlstrøm   +8 more
doaj   +1 more source

Sex differences in clinical cognitive impairment with Lewy bodies: a Chinese multicenter study

Biology of Sex Differences, 2022
Highlights There are significant sex differences in Chinese population with cognitive impairment in Lewy body disease. Women were more common in dementia with Lewy bodies and mild cognitive impairment with Lewy bodies cases, had more frequent and severe ...
Jinghuan Gan, Zhichao Chen, Zhihong Shi, Xudong Li, Shuai Liu, Yiming Liu, Hongcan Zhu, Lu Shen, Guili Zhang, Yong You, Qihao Guo, Nan Zhang, Yang Lv, Baozhi Gang, Junliang Yuan, Yong Ji   +15 more
doaj   +1 more source

Improving the diagnosis and management of Lewy body dementia: the DIAMOND-Lewy research programme including pilot cluster RCT

Programme Grants for Applied Research, 2021
Background: Lewy body dementia, comprising both dementia with Lewy bodies and Parkinson’s disease dementia, is the second commonest cause of neurodegenerative dementia.
John T O’Brien, John-Paul Taylor, Alan Thomas, Claire Bamford, Luke Vale, Sarah Hill, Louise Allan, Tracy Finch, Richard McNally, Louise Hayes, Ajenthan Surendranathan, Joseph Kane, Alexandros E Chrysos, Allison Bentley, Sally Barker, James Mason, David Burn, Ian McKeith   +17 more
doaj   +1 more source

Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports [PDF]

, 2020
Introduction: Since vascular endothelial growth factor (VEGF) regulates several aspects of the central nervous system, particularly in dopaminergic neurons, VEGF inhibitors may be linked to Parkinson-like events and dementia, or variants of these ...
Avery, Bergvall, Caballero, Campochiaro, Cutroneo, de Jong, De Rossi, Evans, Ferrara, Ferrara, Kumar, Lim, Lindquist, McColl, Meyer, Robinson, Sanchez, Sharma, Sheikh, Simó, Steen, Storkebaum, Sultana, Thulliez, Tian, Trifirò, Ueta, Wong, Yasuhara, Ylä-Herttuala, Zachary   +30 more
core   +4 more sources

Behavioral and psychological symptoms in neurodegenerative dementias: harbinger, follower, or constant collateral?

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022
Neurodegenerative dementias such as the behavioral variant of frontotemporal dementia, Alzheimer’s disease, and Parkinson’s disease dementia are linked to various behavioral and psychological abnormalities.
Souvik Dubey, Mahua Jana Dubey, Ritwik Ghosh, Debaleena Mukherjee, Alak Pandit, Julian Benito-León   +5 more
doaj   +1 more source

A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

Nature Communications, 2020
The substantia nigra is important in neurological disease, particularly movement disorders. Here the authors provide a single cell transcriptomic atlas for the human substantia nigra.
Devika Agarwal, Cynthia Sandor, Viola Volpato, Tara M. Caffrey, Jimena Monzón-Sandoval, Rory Bowden, Javier Alegre-Abarrategui, Richard Wade-Martins, Caleb Webber   +8 more
doaj   +1 more source

Mild Cognitive Impairment in Parkinson's Disease - What Is It? [PDF]

, 2018
PURPOSE OF REVIEW: Mild cognitive impairment is a common feature of Parkinson’s disease, even at the earliest disease stages, but there is variation in the nature and severity of cognitive involvement and in the risk of conversion to Parkinson’s disease ...
Costantini, A, Schrag, A, Weil, RS
core   +1 more source

What Can Quantitative Gait Analysis Tell Us about Dementia and Its Subtypes? A Structured Review [PDF]

, 2017
Distinguishing dementia subtypes can be difficult due to similarities in clinical presentation. There is increasing interest in discrete gait characteristics as markers to aid diagnostic algorithms in dementia.
Galna, Brook, Mc Ardle, Ríona, Morris, Rosie, Rochester, Lynn, Thomas, Alan J., Wilson, Joanna   +5 more
core   +2 more sources

Road proximity, air pollution, noise, green space and neurologic disease incidence: a population-based cohort study

Environmental Health, 2020
Background Emerging evidence links road proximity and air pollution with cognitive impairment. Joint effects of noise and greenness have not been evaluated.
Weiran Yuchi, Hind Sbihi, Hugh Davies, Lillian Tamburic, Michael Brauer   +4 more
doaj   +1 more source

Survival and years of life lost in various aetiologies of dementia, mild cognitive impairment (MCI) and subjective cognitive decline (SCD) in Norway. [PDF]

PLoS ONE, 2018
INTRODUCTION:Alzheimer's disease patients are reported to have higher survival rate compared to patients with vascular dementia or dementia with Lewy bodies.
Bjørn Heine Strand, Anne-Brita Knapskog, Karin Persson, Trine Holt Edwin, Rachel Amland, Marit Mjørud, Espen Bjertness, Knut Engedal, Geir Selbæk   +8 more
doaj   +1 more source