Results 21 to 30 of about 125,678 (274)

SORL1 mutation in a Greek family with Parkinson's disease and dementia

Annals of Clinical and Translational Neurology, 2021
Whole exome sequencing and linkage analysis were performed in a three generational pedigree of Greek origin with a broad phenotypic spectrum spanning from Parkinson’s disease and Parkinson’s disease dementia to dementia of mixed type (Alzheimer disease ...
Georgia Xiromerisiou, Thomas Bourinaris, Henry Houlden, Patrick A. Lewis, Konstantin Senkevich, Monia Hammer, Monica Federoff, Alaa Khan, Cleanthe Spanaki, Georgios M. Hadjigeorgiou, Sevasti Bonstanjopoulou, Liana Fidani, Aleksey Ermolaev, Ziv Gan‐Or, Andrew Singleton, Jana Vandrovcova, John Hardy   +16 more
doaj   +1 more source

Cognitive impairment in Parkinson's disease : is it a unified phenomenon? [PDF]

, 2005
Parkinson's disease (PD) has long been associated with dementia. This has been found to correlate with participant age, age at onset of PD and severity of PD.
Brendel, Bettina, Howell, Peter, Lowit, Anja   +2 more
core   +1 more source

Cortical Lewy Body Dementia

Behavioural Neurology, 1990
In cortical Lewy body dementia the distribution of Lewy bodies in the nervous system follows that of Parkinson's disease, except for their greater profusion in the cerebral cortex. The cortical tangles and plaques of Alzheimer pathology are often present,
W. R. G. Gibb
doaj   +1 more source

Mild behavioral impairment in Parkinson's disease: Data from the Parkinson's disease cognitive impairment study (PACOS) [PDF]

, 2019
Neuropsychiatric symptoms (NPS) have been frequently described in Parkinson's disease (PD), even in the earliest stages of the disease. Recently the construct of mild behavioral impairment (MBI) has been proposed as an at-risk state for incident ...
Baschi R., Cicero C. E., Luca A., Monastero R., Nicoletti A., Recca D., Restivo V., Zappia M.   +7 more
core   +1 more source

Identification of the sites of tau hyperphosphorylation and activation of tau kinases in synucleinopathies and Alzheimer's diseases.

PLoS ONE, 2013
ObjectiveMost neurodegenerative diseases contain hyperphosphorylated Tau [p-Tau]. We examined for the first time epitopes at which Tau is hyperphosphorylated in Parkinson's disease, dementia with Lewy bodies and Alzheimer's disease, and also select Tau ...
Valeriy Duka, Jae-Hoon Lee, Joel Credle, Jonathan Wills, Adam Oaks, Ciaran Smolinsky, Ketul Shah, Deborah C Mash, Eliezer Masliah, Anita Sidhu   +9 more
doaj   +1 more source

Recognition by familiarity is preserved in Parkinson's without dementia and Lewy-Body disease [PDF]

, 2013
Objective: The retrieval deficit hypothesis states that the lack of deficit in recognition often observed in patients with Parkinson's disease is because of the low retrieval requirements of the task, given that these patients have retrieval and not ...
Algarabel González, Salvador, Rodríguez, Lucía-Azahara, Escudero, Joaquín, Fuentes, Manuel, Peset, Vicente, Pitarque, Alfonso, Cómbita, Lina-Marcela, Mazón Herrero, José Francisco   +7 more
core   +1 more source

Clinical characteristics with an impact on ADL functions of PD patients with cognitive impairment indicative of dementia. [PDF]

PLoS ONE, 2013
BackgroundDementia in Parkinson's disease (PD) is defined as cognitive decline severe enough to affect activities of daily living function (ADL). The aim of our exploratory study was to compare two groups of PD patients.
Inga Liepelt-Scarfone, Monika Fruhmann Berger, Deborah Prakash, Ilona Csoti, Susanne Gräber, Walter Maetzler, Daniela Berg   +6 more
doaj   +1 more source

Demência na doença de Parkinson Dementia in Parkinsn's disease

Brazilian Journal of Psychiatry, 2008
OBJETIVO: A presença de síndromes psiquiátricas, incluindo demência, associada a distúrbios motores tem sido cada vez mais reconhecida durante a última década, com destaque para o prejuízo cognitivo na doença de Parkinson idiopática.
Leonardo Caixeta, Renata Teles Vieira
doaj   +1 more source

Dementia and Parkinson's Disease: Similar and Divergent Challenges in Providing Palliative Care

Frontiers in Neurology, 2019
Dementia and Parkinson's disease are incurable neurological conditions. Patients often experience specific, complex, and varying needs along their disease trajectory. Current management typically employs a multidisciplinary team approach.
Jenny T. van der Steen, Jenny T. van der Steen, Herma Lennaerts, Danny Hommel, Danny Hommel, Bertie Augustijn, Marieke Groot, Jeroen Hasselaar, Bastiaan R. Bloem, Raymond T. C. M. Koopmans, Raymond T. C. M. Koopmans, Raymond T. C. M. Koopmans   +11 more
doaj   +1 more source

Additional file 3: of Meta-analysis of risk factors for Parkinsonâ s disease dementia

, 2016
Details of factors not included in the meta-analysis. This file provided data of risk factors for Parkinsonâ s disease dementia that were mentioned in literature, but were not included in the meta-analysis due to limited number of studies or differences in study design. (DOCX 93 kb)
Yaqian Xu, Yang, Jing, Huifang Shang
openaire   +1 more source