Results 151 to 160 of about 223,878 (259)

Eye-Tracking Assessment of Visual, Oculomotor, and Pupillary Biomarkers During Reading in Parkinson's Disease. [PDF]

Life (Basel)
Cabrera-Guardiola I, Herrero-Gracia A, El-Asmak-El-Harrak A, Arcas-Carbonell M, Sanchez-Cano A, Díez-Ajenjo MA, Orduna-Hospital E.   +6 more
europepmc   +1 more source

George Washington, Statement of Richard Parkinson, Lincolnshire Farmer, 1909

, 1909
Extracts from Richard Parkinson's "A tour in America in 1798, 1799 and 1800". Parkinson generally disliked what he saw of America. The editor says that Parkinson's "impressions of George Washington are perhaps all the more interesting from the fact of ...
Morrison, Alfred J. (Alfred James), 1876-1923
core  

α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths

Advanced Science, EarlyView.
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel, Soumik Ray, Federica Saraceno, Giacomo Nisini, Georgia Nasi, Thomas Oliver Mason, Antonin Kunka, Effrosyni Agrimaki, Dannie Juul Olesen, Francesco Simone Ruggeri, Alexander K. Buell   +10 more
wiley   +1 more source

Explicit Mechanistic Causal Analyses or Interventional Trials Are Required for Objective, Clinical, Voice-Based Parkinson Disease Characterization. [PDF]

J Med Internet Res
Little M.
europepmc   +1 more source

Oral History Interview: Kathryn Parkinson (0379)

, 1990
Background; Attending UW; Music major; Grandfather John Parkinson; Courses; Interest in music; Proms and other dances; Langdon, Murray and State Streets; Appearance of UW campus in early 1900s; Kappa Kappa Gamma sorority; Professors Carl Fish, Benjamin ...

core  

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

The Fascination of the Wolff-Parkinson-White Syndrome. [PDF]

Arq Bras Cardiol
Brugada P.
europepmc   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

Advanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee, Chanju Jung, Minjeong Kim, Narae Kim, Gue‐Ho Hwang, Soon‐Tae Lee, Kon Chu, Sang Kun Lee, Han‐Joon Kim, Jong‐Hee Chae, Sangsu Bae, Jangsup Moon   +11 more
wiley   +1 more source

Incidental Wolff-Parkinson-White Syndrome Discovered Following Dicyclomine Use: A Case Report. [PDF]

Clin Pract Cases Emerg Med
Wahhab J, Loveridge N, Siaj M.
europepmc   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source