Results 161 to 170 of about 496,828 (359)

Parkinsonism

Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2007
openaire   +3 more sources

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Reevaluation von Patienten mit klinischem Verdacht auf Morbus Parkinson und unauffälliger Bildgebung des präsynaptischen dopaminergen Systems

, 2010
Dominik Neukirch
openalex   +2 more sources

The Right to Economic Development in International Law [PDF]

, 1984
Parkinson, F.
core   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Konzeption, Entwicklung und Evaluation eines interoperablen Telemonitoringsystems für Patienten mit Morbus Parkinson

, 2017
Neltje Emma Piro
openalex   +2 more sources

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Reviewer #1 (Public Review): Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model

Behzad Yaghmaeian Salmani, Laura Lahti, Linda Gillberg, Jesper Kjaer Jacobsen, Ioannis Mantas, Per Svenningsson, Thomas Perlmann   +6 more
openalex   +1 more source

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

Advanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul, Aiyarin Kittilukkana, Luis C. C. Huarte, Hiram Castillo‐Michel, Murielle Salome, Stéphane Roudeau, Pauline Belzanne, Matthieu Sainlos, Noémie Pied, Monica Fernandez‐Monreal, Daniel Choquet, Richard Ortega, Asuncion Carmona   +12 more
wiley   +1 more source

The Financial and Environmental Cost of Anaesthetic Emergency Drugs: Comparing Ampoules With Prefilled Syringes. [PDF]

Cureus
Parkinson EA, Plews E, Hewavitharane C, Catchpole G, Nunoo RA, Arora H, Chapman C.   +6 more
europepmc   +1 more source