Results 181 to 190 of about 496,828 (359)

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Periodontal inflammation and tryptophan-kynurenine metabolism in Parkinson's disease. [PDF]

Clin Oral Investig
Yilmaz M, Bakici A, Parlat R, Akpinar İN, Karaaslan R, Balci N, Toygar H, Kurgan Ş, Serdar MA, Kantarcı A.   +9 more
europepmc   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Exploring the molecular mechanisms by which exercise improves cognitive impairment in Parkinson's disease based on the brain-gut microbiota axis: bibliometrics and visualization analysis. [PDF]

Front Microbiol
Wang W, Ma T, Qiu Z, Zhang X, Sun W.
europepmc   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Ultrastructural and chemical analysis of human Locus coeruleus using correlative microscopy and mass spectrometry [PDF]

BIO Web of Conferences
Berro Zahraa, Subirana Maria Angels, Warres Clementine, Wirtz Tom, Taubitz Tatjana, Audinot Jean-Nicolas, Zucca Fabio A., Mittelbronn Michel, Zecca Luigi, Biesemeier Antje   +9 more
doaj   +1 more source

A Synergistic Hydrogel‐Microalgae Platform for Dual‐Targeting of Intestinal and Neuroimmune Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
A bioactive hydrogel incorporating Chlorella vulgaris and paeoniflorin within a carboxymethyl chitosan/sodium alginate matrix cross‐linked with genipin is developed for inflammatory bowel disease therapy. The hydrogel exhibits gastric stability and intestine‐responsive release.
Jing Lu, Kangyu Jin, Bing Chen, Ruoxi Wang, Fengling Hu, Shaohua Hu, Danni Zhong, Xiaoming Li, Min Zhou   +8 more
wiley   +1 more source

Characteristics of Tremorogenesis and Tremorolytic Agents in a Pharmacological Rodent Model of Parkinsonism: Evidence from Behavioral, Neurochemical, and Electrophysiological Studies

, 2015
Samantha J. Podurgiel
openalex   +1 more source

Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference [PDF]

, 1997
Norman L. Foster, Kirk C. Wilhelmsen, Anders A. F. Sima, M. Z. Jones, Constance J. D’Amato, Sid Gilman, Conference Participants   +6 more
openalex   +1 more source

Orthogonal Ionic Liquid‐Based Extraction Strategy Enables Amyloid‐Specific Profiling of Aggregate Proteome

Advanced Science, EarlyView.
An orthogonal ionic‐liquid extraction (Orth‐iEA) enables selective isolation of amyloid fibrils. TMGBF4 disrupts hydrogen‐bonded β‐sheet networks to solubilize amyloid aggregates, whereas C12ImCl interacts with hydrophobic regions of non‐amyloid proteins.
Shiying Zheng, Ye Liu, Bowen Zhong, Huiying Chu, Zhou Gong, Baofeng Zhao, Mengchun Cheng, Zhen Liang, Yukui Zhang, Qun Zhao, Lihua Zhang   +10 more
wiley   +1 more source