Exploring the molecular mechanisms by which exercise improves cognitive impairment in Parkinson's disease based on the brain-gut microbiota axis: bibliometrics and visualization analysis. [PDF]
Front MicrobiolWang W, Ma T, Qiu Z, Zhang X, Sun W.
europepmc +1 more source
Has Inequity Faced by Young Australians With Disability Changed Since the Turn of the Century?
Australian Journal of Social Issues, EarlyView.ABSTRACT Despite the introduction of various policies aimed at promoting equality for people with disability since Australia ratified the Convention on the Rights of People with Disabilities (CRPD) in 2008, there has been little evaluation regarding the extent of change in inequity since then.
Asha Parkinson +5 more
wiley +1 more source
Effects of a Soft Robotic Exoskeleton for Gait Training on Clinical Outcomes in Patients With Parkinson Disease: Randomized Controlled Pilot Study. [PDF]
J Med Internet ResBu S, Luo X, Li S, Shi Y, Jin L, Zhao Q.
europepmc +1 more source
Associations Between Multiple Chemosensory Dysfunction and Cognition
International Forum of Allergy &Rhinology, EarlyView.Key Points This study supports the association between chemosensory dysfunction and cognition. We introduce methods of assessing trigeminal function with the Medoc TSA‐II thermoprobe. Our results identify an association between subjective trigeminal dysfunction and cognition.
Michelle Yu +5 more
wiley +1 more source
Causal relationship between intervertebral disc degeneration and neurological disorders: A Mendelian randomization study. [PDF]
Medicine (Baltimore)Cao X.
europepmc +1 more source
Animal Models and Experimental Medicine, EarlyView.The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad +9 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.At the genomic level, a large number of differentially expressed genes (DEGs) and aging‐related DEGs have been screened. Ten hub genes, such as IFNγ and IRF7, have been identified and shown potential value in the diagnosis of PD, holding promise as novel biomarkers to facilitate early and precise diagnosis.
Haojie Wu +3 more
wiley +1 more source
Myocardial work efficiency in children with Wolff-Parkinson-White preexcitation before and after accessory pathway ablation. [PDF]
Front Cardiovasc MedHadžić T +6 more
europepmc +1 more source
Single‐cell atlas of neuroglial dynamics in SNCA‐A53T Parkinson's disease mouse model
Animal Models and Experimental Medicine, EarlyView.We performed single‐cell RNA sequencing of midbrain and striatal tissues from SNCA‐A53T Parkinson's disease (PD) mice, revealing glia‐enriched PD‐risk gene signatures and disease‐specific subpopulations. Transcriptional dysregulation of key TFs (e.g., Rorb, Foxc1) and enhanced neuroinflammatory signaling (SEMA, CCL, MIF) were identified.
Binqing Qin +7 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.
Petr Krýže +17 more
wiley +1 more source