Results 41 to 50 of about 496,828 (359)

Handwriting analysis for diagnosis and prognosis of Parkinson’s disease [PDF]

, 2010
At present, there are no quantitative, objective methods for diagnosing the Parkinson disease. Existing methods of quantitative analysis by myograms suffer by inaccuracy and patient strain; electronic tablet analysis is limited to the visible drawing ...
Brause, Rüdiger W., Krakow, Karsten, Ünlü, Atilla   +2 more
core  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

The Effect of Ethanolic The effect of ethanolic extract of Saffron (Crocus sativus L.) on improving the spatial memory parameters in the experimental models of Parkinson disease in male rats [PDF]

Journal of Advanced Biomedical Sciences, 2015
Background & Objective: The axial role of the oxidative stress in the pathophysiology of Parkinson disease has been identified. On the other hand, the learning and memory impairment in Parkinson disease has a distinguished outlook.
Homeyra Hatami, Gholamreza Dehghan
doaj  

Thai national guideline for nuclear medicine investigation in movement disorders: Nuclear medicine society of Thailand, the neurological society of Thailand, and Thai medical physicist society collaboration [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology
Movement disorders are chronic neurological syndromes with both treatable and non-treatable causes. The top causes of movement disorders are Parkinson's disease and related disorders. Functional imaging investigations with Single Photon Emission Computed
Tawika Kaewchur, Benjapa Khiewvan, Wichana Chamroonrat, Praween Lolekha, Onanong Phokaewvarangkul, Tanyaluck Thientunyakit, Nantaporn Wongsurawat, Peerapon Kiatkittikul, Chanisa Chotipanich, Wen-Sheng Huang, Panya Pasawang, Tanawat Sontrapornpol, Nucharee Poon-iad, Sasithorn Amnuaywattakorn, Supatporn Tepmongkol   +14 more
doaj   +1 more source

Lacunes may worsen cognition but not motor function in Parkinson's disease

Brain and Behavior, 2023
Background As one of the imaging markers of cerebral small vessel disease, lacunes has received little attention. The objective of this study was to investigate the associations of lacunes, cognition and motor function in patients with Parkinson's ...
Keke Chen, Zhaohui Jin, Jinping Fang, Lin Qi, Cui Liu, Ruidan Wang, Yuan Su, Hongjiao Yan, Aixian Liu, Jianing Xi, Boyan Fang   +10 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Native α-Synuclein, 3-Nitrotyrosine Proteins, and Patterns of Nitro-α-Synuclein-Immunoreactive Inclusions in Saliva and Submandibulary Gland in Parkinson’s Disease

Antioxidants, 2021
Background. Salivary α-synuclein (aSyn) and its nitrated form, or 3-nitrotyrosine-α-synuclein (3-NT-αSyn), hold promise as biomarkers for idiopathic Parkinson’s disease (IPD).
Emilio Fernández-Espejo, Fernando Rodríguez de Fonseca, Juan Suárez, Eduardo Tolosa, Dolores Vilas, Iban Aldecoa, Joan Berenguer, Fátima Damas-Hermoso   +7 more
doaj   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Simultaneous treatment with cells and rosemary extract ameliorates 6-OHDA-induced toxicity in the hippocampus of mice

Journal of Advanced Pharmaceutical Technology & Research
In this study, we delved into the hippocampal region to understand the effects of adipose stem cells (ADSCs) and rosemary extract (RE). Our main objective was to explore how these substances influence spatial memory, neurotrophins, and changes in ...
Aboutaleb Kousha, Gholamhassan Vaezi, Maryam Haji Ghasem Kashani, Vida Hojati   +3 more
doaj   +1 more source

Fermi-LAT searches for gamma-ray pulsars

, 2012
The Large Area Telescope (LAT) on the Fermi satellite is the first gamma-ray instrument to discover pulsars directly via their gamma-ray emission. Roughly one third of the 117 gamma-ray pulsars detected by the LAT in its first three years were discovered
Parkinson, Pablo M. Saz
core   +1 more source