Results 21 to 30 of about 223,878 (259)

Evaluation of antiparkinsonian activity of water yam tuber (Dioscorea alata L.) extract on haloperidol-induced Parkinson’s disease in mice [PDF]

open access: yesPharmaciana, 2023
Parkinson’s disease (PD) appears as motor dysfunction that is attributed to depleting dopamine levels due to cell death in the extrapyramidal system that is comprised of the basal ganglia’s motor neurons.
Sapto Yuliani   +5 more
doaj   +1 more source

Comparison of the Effects of Exercise Intensity on Learning, Spatial Memory and Anxiety Behaviors in Rats with Motion Impairment [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی, 2018
The role of the training is to improve the symptoms of Parkinson's disease. The purpose of this study was to compare the effects of exercise intensity on learning, spatial memory and anxiety behaviors in rat with impair . In this study, 24 male rats were
Zahra Soori, Ali Heyrani, Rahman Souri
doaj   +1 more source

Exploring the multifaceted neuroprotective actions of gallic acid: a review

open access: yesInternational Journal of Food Properties, 2020
Much attention has been recently given to the effect of diet compounds on physical and mental health. Gallic acid is a phenolic compound with antioxidant activity.
Sahreh Shabani   +2 more
doaj   +1 more source

Intermittent theta-burst stimulation combined with physical therapy as an optimal rehabilitation in Parkinson’s disease: study protocol for a randomised, double-blind, controlled trial

open access: yesTrials, 2023
Background First-line rehabilitative strategies to improve motor deficits are based on functional training (physical or occupational therapy), which has been demonstrated to facilitate neural reorganisation.
Zhao-hui Jin   +17 more
doaj   +1 more source

Constitutively active STING causes neuroinflammation and degeneration of dopaminergic neurons in mice

open access: yeseLife, 2022
Stimulator of interferon genes (STING) is activated after detection of cytoplasmic dsDNA by cGAS (cyclic GMP-AMP synthase) as part of the innate immunity defence against viral pathogens. STING binds TANK-binding kinase 1 (TBK1).
Eva M Szego   +5 more
doaj   +1 more source

Ambroxol therapy for Parkinson’s disease: Systematic literature review [PDF]

open access: yesRomanian Journal of Neurology, 2023
Parkinson’s disease (PD) is the second most common neurodegenerative disease. The accumulation of α-synuclein protein in the basal ganglia is the underlying pathogenesis of PD. Genetic abnormalities are one of the predisposing factors for PD.
Virgi Mayang Maharani   +3 more
doaj   +1 more source

Efectividad de tres métodos de estimación de edad dental en personas adultas vivas - Región Huánuco

open access: yesRevista Peruana de Ciencias de la Salud, 2023
Objetivo. Determinar la efectividad de tres métodos de estimación de edad dental en personas adultas vivas de la región de Huánuco. Métodos. Fue una investigación aplicada de diseño transversal, a partir de un estudio correlacional, comparativo, de ...
Ronald Christian Solís Adrianzèn
doaj   +1 more source

Influencia de la microbiota intestinal en la enfermedad de Parkinson. Revisión

open access: yesRevista Peruana de Ciencias de la Salud, 2023
El objetivo del presente estudio es analizar el papel de la microbiota intestinal en la progresión de la enfermedad de Parkinson, realizando una revisión bibliográfca.
Alejandra Belen Maldonado Gomez   +3 more
doaj   +1 more source

Microglial Phagocytosis and Its Regulation: A Therapeutic Target in Parkinson’s Disease?

open access: yesFrontiers in Molecular Neuroscience, 2018
The role of phagocytosis in the neuroprotective function of microglia has been appreciated for a long time, but only more recently a dysregulation of this process has been recognized in Parkinson’s disease (PD).
Elzbieta Janda, Laura Boi, Anna R. Carta
doaj   +1 more source

The Role of Ca2+ Signaling in Aging and Neurodegeneration: Insights from Caenorhabditis elegans Models

open access: yesCells, 2020
Ca2+ is a ubiquitous second messenger that plays an essential role in physiological processes such as muscle contraction, neuronal secretion, and cell proliferation or differentiation.
Javier Alvarez   +4 more
doaj   +1 more source

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