Results 71 to 80 of about 693,546 (355)

Sarcopenia in Patients With Parkinson's Disease: A Systematic Review and Meta-Analysis

Frontiers in Neurology, 2021
Background: Parkinson's disease (PD) and sarcopenia are two common diseases in aging people. To date, the prevalence of sarcopenia in PD patients and the relationship between clinical features and sarcopenia in PD patients are not clear.
Yingying Cai, Fei Feng, Q. Wei, Zheng Jiang, R. Ou, H. Shang   +5 more
semanticscholar   +1 more source

Validation of Secondary Data Sources to Identify Parkinson Disease Against Clinical Diagnostic Criteria [PDF]

American Journal of Epidemiology, 2014
Parkinson disease (PD) is the second most common neurodegenerative disorder. Its diagnosis relies solely on a clinical examination and is not straightforward because no diagnostic test exists. Large, population-based, prospective cohort studies designed to examine other outcomes that are more common than PD might provide cost-efficient alternatives for
Samay, Jain, Jayandra, Himali, Alexa, Beiser, Thanh G N, Ton, Margaret, Kelly-Hayes, Mary Lou, Biggs, Joseph A C, Delaney, Caterina, Rosano, Sudha, Seshadri, Samuel A, Frank   +9 more
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study.

Brain : a journal of neurology, 2020
Parkinson's disease is characterized by the presence of abnormal, intraneuronal α-synuclein aggregates, which may propagate from cell-to-cell in a prion-like manner. However, it remains uncertain where the initial α-synuclein aggregates originate.
Jacob Horsager, Katrine B. Andersen, K. Knudsen, Casper Skjærbæk, T. Fedorova, N. Okkels, E. Schaeffer, Sarah K Bonkat, J. Geday, M. Otto, M. Sommerauer, E. Danielsen, E. Bech, Jonas Kraft, O. Munk, Sandra D Hansen, N. Pavese, R. Göder, D. Brooks, D. Berg, P. Borghammer   +20 more
semanticscholar   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Balance differences in people with Parkinson disease with and without freezing of gait [PDF]

, 2015
Published in final edited form as: Gait Posture. 2015 September ; 42(3): 306–309. doi:10.1016/j.gaitpost.2015.06.007.BACKGROUND: Freezing of gait (FOG) is a relatively common and remarkably disabling impairment associated with Parkinson disease (PD).
Cavanaugh, James T., Dibble, Leland E., Duncan, Ryan P., Earhart, Gammon M., Ellis, Terry D., Ford, Matthew P., Foreman, K. Bo, Leddy, Abigail L.   +7 more
core   +1 more source

The Add-On Effect of Lactobacillus plantarum PS128 in Patients With Parkinson's Disease: A Pilot Study

Frontiers in Nutrition, 2021
Background: Lactobacillus plantarum PS128 (PS128) is a specific probiotic, known as a psychobiotic, which has been demonstrated to alleviate motor deficits and inhibit neurodegenerative processes in Parkinson's disease (PD)-model mice.
C. Lu, Hsiu-Chen Chang, Y. Weng, Chiung-Chu Chen, Yi-Shan Kuo, Y. Tsai   +5 more
semanticscholar   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster, Jae Woo Chung, Maria E. Linn‐Evans, Matthew N. Petrucci, Chiahao Lu, Destiny J. Weaver, Joshua De Kam, Scott E. Cooper, Paul J. Tuite, Aleksandar Videnovic, Michael J. Howell, Colum D. MacKinnon   +11 more
wiley   +1 more source

Weight faltering and failure to thrive in infancy and early childhood [PDF]

, 2012
Weight faltering, or failure to thrive, is a childhood condition that provokes concern about possible neglect, deprivation, and organic illness. However, research over the past 20 years has brought the validity of this concern into question, leading to ...
Shields, B., Wacogne, I., Wright, C.M.
core   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source