Results 91 to 100 of about 9,346,254 (401)
The Value of Multidisciplinary Care in Parkinson\u27s Disease [PDF]
, 2003 Educational Objectives 1. To recognize the signs and symptoms of Parkinson\u27s disease (PD). 2. To identify key treatment and management strategies for PD. 3.
Baron, Mark, Hirsch, Miriam
core +1 more source
Parkinson disease-associated cognitive impairment
Nature Reviews Disease Primers, 2021 D. Aarsland +6 more
semanticscholar +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo +11 more
wiley +1 more source
Trials, 2018 Introduction Recruitment of sufficient patients with Parkinson disease into clinical trials is a barrier to successful, timely study completion. Non-pharmacologic studies have shown to be even more challenging for recruitment, despite some studies ...
Deborah A. Hall +3 more
doaj +1 more source
PHEN : parkinson helper emergency notification system using Bayesian Belief Network [PDF]
, 2015 Context-aware systems are used to aid users in their daily lives. In the recent years, researchers are exploring how context aware systems can benefit humanity through assist patients, specifically those who suffer incurable diseases, to cope with their ...
Khreiss, Malak +3 more
core +2 more sources
Paroxysmal Dyskinesias Secondary to HHV‐6A Encephalitis: The First Case Report and Literature Review
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias.
Zhuoran Wang +5 more
wiley +1 more source
Central and peripheral α‐synuclein in Parkinson disease detected by seed amplification assay
Annals of Clinical and Translational Neurology, 2023 Objectives Detection of α‐synuclein aggregates by seed amplification is a promising Parkinson disease biomarker assay. Understanding intraindividual relationships of α‐synuclein measures could inform optimal biomarker development.
Lana M. Chahine +15 more
doaj +1 more source
Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation [PDF]
, 2016 Endosomal sorting is a highly orchestrated cellular process. Retromer is a heterotrimeric complex that associates with endosomal membranes and facilitates the retrograde sorting of multiple receptors, including the cation-independent mannose 6-phosphate ...
Ariotti, Nicholas +7 more
core +1 more source
Serum neuronal exosomes predict and differentiate Parkinson’s disease from atypical parkinsonism
Journal of Neurology Neurosurgery & Psychiatry, 2020 Objective Parkinson’s disease is characterised neuropathologically by α-synuclein aggregation. Currently, there is no blood test to predict the underlying pathology or distinguish Parkinson’s from atypical parkinsonian syndromes. We assessed the clinical
Cheng Jiang +16 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous neurodegenerative diseases causing progressive deterioration and reduced quality of life. Therapeutic advances have been limited by a lack of sensitive anatomic, functional, or diffusion imaging‐based biomarkers.
David J. Arpin +11 more
wiley +1 more source