Results 131 to 140 of about 98,362 (265)
Use of safinamide for treatment of Parkinson disease: real-world data from Spain. [PDF]
Morales Casado MI, López Ariztegui N.
europepmc +1 more source
Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to long term losses of dopamine neurons in offspring a potential new model of parkinson s disease [PDF]
Paul M. Carvey+3 more
openalex +1 more source
Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis
This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu+9 more
wiley +1 more source
Data-Driven Subtypes of Parkinson Disease Based on Dopamine Responsiveness. [PDF]
Wang JY+14 more
europepmc +1 more source
Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics
Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan+12 more
wiley +1 more source
Effect of levodopa on interleukin‐15 and RANTES circulating levels in patients affected by Parkinson′s disease [PDF]
Sebastiano Gangemi+7 more
openalex +1 more source
Soft robotics, featuring intrinsic compliance and biomimetic adaptability, emerges as transformative in next‐generation intelligent systems. This review outlines how advancements in four foundational domains—actuation, materials, manufacturing, and control—drive the evolution of bioinspired intelligent soft robotics, poised to redefine the boundaries ...
Xiaopeng Wang+7 more
wiley +1 more source