Results 201 to 210 of about 274,716 (345)

Oral Exposure to Food‐Grade Nanoparticles Poses a Risk of Alzheimer's Disease‐Like Symptoms by Triggering Autophagy Defects in Neurons

Advanced Science, EarlyView.
Three food‐grade nanomaterials induce dysregulated RyR‐Ca2+ signaling through epigenetic modifications. This dysregulation impairs the autophagic clearance process, ultimately leading to abnormal Aβ deposition and increase phosphorylated tau levels.
Jiaxin Shang, Jun Yan, He Lou, Xuanxi Jiang, Ziyue Wang, Yue Gao, Xiaohui Fan, Xiaoyan Lu   +7 more
wiley   +1 more source

Stochastic resonance stimulation effect on stability during walking in people with Parkinson disease. [PDF]

Int Biomech
Alsaqabi E, DiBianca S, Sansare A, Verma K, Reimann H, Jeka J.   +5 more
europepmc   +1 more source

Supplementary motor area stimulation for Parkinson disease: A randomized controlled study [PDF]

, 2013
Vesper Ramos, Rainer W. Paine, Nivethida Thirugnanasambandam   +2 more
openalex   +1 more source

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

Advanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn, Soyeon Chang, Jiyoung Lee, Seok‐Ho Choi, Jinju Han, Yangsik Kim   +5 more
wiley   +1 more source

Effects of Ketogenic Diet on Quality of Life in Parkinson Disease: An Integrative Review. [PDF]

Nutrients
Golob MG, Mancin S, Lopane D, Coldani C, Cattani D, Dacomi A, Tomaiuolo G, Petrelli F, Cangelosi G, Cosmai S, Santagostino AM, Mazzoleni B.   +11 more
europepmc   +1 more source

Evidence-based treatment of voice and speech disorders in Parkinson disease

, 2015
Leslie Mahler, Lorraine O. Ramig, Cynthia Fox   +2 more
openalex   +2 more sources

Phase determination using chromosomal microarray and fluorescence in situ hybridization in a patient with early onset Parkinson disease and two deletions in PRKN [PDF]

, 2018
Eli S. Williams, Matthew J. Barrett, Radhika Dhamija, Lisa Toran, Chelsea Chambers, Mani S. Mahadevan, Wendy L. Golden   +6 more
openalex   +1 more source

Parkinson's disease. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1990
openaire   +5 more sources

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Morphological and Hyperphosphorylation Transitions of Nanoscale Tau Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
Super‐resolution microscopy identifies nano‐sized tau aggregates (nano‐aggregates) and reveals distinct transitions in their morphology and phosphorylation profiles across control, Primary Age‐Related Tauopathy, and Alzheimer's disease brains. Morphology and hyperphosphorylation signatures distinguish physiological from pathological forms, with nano ...
Adriana N. Santiago‐Ruiz, Siewert Hugelier, Gabriela L. Correa, Charles R. Bond, Edward B. Lee, Melike Lakadamyali   +5 more
wiley   +1 more source