Results 201 to 210 of about 9,346,254 (401)

Modeling of the Sedative and Airway Obstruction Effects of Propofol in Patients with Parkinson Disease undergoing Stereotactic Surgery [PDF]

, 2002
Neus Fàbregas, Javier Rapado, Pedro L. Gambús, R. Valero, Enrique Carrero, Lydia Salvador, Miguel A. Nalda-Felipe, Iñaki F. Trocóniz   +7 more
openalex   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Pramipexole vs Levodopa as Initial Treatment for Parkinson Disease

, 2000
Parkinson Study Group
openalex   +1 more source

Applications of neural network analyses to in vivo ¹H magnetic resonance spectroscopy of Parkinson disease patients [PDF]

, 2002
David E. Axelson, Inger Johanne Bakken, Ingrid S. Gribbestad, Benny Ehrnholm, Gunnar Nilsen, Jan Aasly   +5 more
openalex   +1 more source

The genetic architecture of Parkinson's disease

Lancet Neurology, 2020
C. Blauwendraat, M. Nalls, A. Singleton
semanticscholar   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

Advanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He, Zhidong Wei, Jianda Xu, Fei Jin, Tong Li, Lili Qian, Juan Ma, Weiying Zheng, Negar Javanmardi, Ting Wang, Kangjian Sun, Zhang‐Qi Feng   +11 more
wiley   +1 more source

Selective neuronal vulnerability in Parkinson disease

Nature Reviews Neuroscience, 2017
D. Surmeier, J. Obeso, J. Obeso, G. Halliday, G. Halliday   +4 more
semanticscholar   +1 more source

Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation

Advanced Science, EarlyView.
Exogenous alternating current fields are explored and interact with cerebral cortex slow waves in vitro and in silico. Varying frequency and amplitude of sine waves result in distinct network dynamics, from phase‐locking and entrainment to desynchronization. These responses occupy specific regions within the parameter space.
Joana Covelo, Martina Cortada, Gianni V. Vinci, Maurizio Mattia, Maria V. Sanchez‐Vives   +4 more
wiley   +1 more source

Cognitive decline in Parkinson disease

Nature Reviews Neurology, 2017
D. Aarsland, B. Creese, M. Politis, K. Chaudhuri, D. Ffytche, D. Weintraub, C. Ballard   +6 more
semanticscholar   +1 more source

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source