Results 201 to 210 of about 9,643,208 (350)

Neuroprotection in Parkinson Disease. [PDF]

open access: yesNeurol Ther
Gonzalez-Robles C   +2 more
europepmc   +1 more source

EXERCISES WITH AND WITHOUT VIRTUAL REALITY ON PAIN IN PATIENTS WITH PARKINSON DISEASE: A RANDOMIZED, CONTROLLED, SINGLE-BLIND TRIAL

open access: diamond, 2017
Matheus Silva d’Alencar   +5 more
openalex   +1 more source

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

open access: yesNature Neuroscience, 2000
R. Betarbet   +5 more
semanticscholar   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

open access: yesAdvanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu   +11 more
wiley   +1 more source

Olfactory Dysfunction as a Window Into the Heterogeneity of Parkinson Disease. [PDF]

open access: yesEur J Neurol
Sun Y   +10 more
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

open access: yesAdvanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong   +5 more
wiley   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

open access: yesAdvanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang   +16 more
wiley   +1 more source

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