Results 91 to 100 of about 65,159 (298)

Oscillations in Pedunculopontine Nucleus in Parkinson's disease and its relationship with deep brain stimulation

Frontiers in Neural Circuits, 2015
The recent development of deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) for the treatment of parkinsonian patients, particularly those in advanced stages with axial symptoms, has ignited interest into the study of this brain nucleus.
Min eLi, Wangming eZhang
doaj   +1 more source

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

Food Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra, Monika Bhadauria, Satendra Kumar Nirala   +2 more
wiley   +1 more source

Reduced locus coeruleus integrity linked to response inhibition deficits in parkinsonian disorders [PDF]

, 2021
Rong Ye, Frank H. Hezemans, Claire O’Callaghan, Kamen A. Tsvetanov, Catarina Rua, P. Simon Jones, Negin Holland, Maura Malpetti, Alexander G. Murley, Roger A. Barker, Caroline H. Williams‐Gray, Trevor W. Robbins, Luca Passamonti, James B. Rowe   +13 more
openalex   +1 more source

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

iNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu, Jinmei Sun, Lili Hu, Xin Chen, Jinying Han, Liuzhenxiong Yu, Siyu Fan, Rong Ye, Kai Wang, Gong‐Jun Ji, Panpan Hu   +10 more
wiley   +1 more source

Trends in Laryngology Fellowship Training: A Survey Study of Graduates and Directors

The Laryngoscope, EarlyView.
A survey study of laryngology fellowship Graduates and Directors reveals overall high level of confidence in preparedness to practice in the care of most laryngologic disorders. Respondents reported less exposure to swallowing disorders in fellowship with resulting lower confidence to practice independently in this area, despite seeing a good ...
Vanessa Torrecillas, Michael M. Johns III, Al Merati, Robbi Kupfer, Robert J. Morrison   +4 more
wiley   +1 more source

Parkinsonian motor impairment predicts personality domains related to genetic risk and treatment outcomes in schizophrenia [PDF]

, 2017
Identifying endophenotypes of schizophrenia is of critical importance and has profound implications on clinical practice. Here we propose an innovative approach to clarify the mechanims through which temperament and character deviance relates to risk for
Alemán, Gabriela González, Balda, Mara, Bourdieu, Mercedes, Calvó, María, Cloninger, C. Robert, Conesa, Horacio A, de Erausquin, Gabriel A, Escobar, Javier I, Florenzano, Néstor V, Guerrero, Gonzalo, Kamis, Danielle, Molina, Juan L, Padilla, Eduardo, Rangeon, Beatriz Molina, Strejilevich, Sergio A, Zwir, Igor   +15 more
core   +2 more sources

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Suppression and treatment of Haloperidol induced extra-pyramidal side effects and anxiety syndrome by the coadministeration of red rice bran oil in rats

International Journal of Endorsing Health Science Research, 2014
Antipsychotic medications may reduce or eliminate symptoms of psychosis. They are not a 'cure' for mental illnesses, but can be an effective part of treating mental disorders.
Farah Naz, Erum Shireen
doaj   +1 more source

Maladaptive plasticity in levodopa-induced dyskinesias and tardive dyskinesias: old and new insights on the effects of dopamine receptor pharmacology. [PDF]

, 2014
Maladaptive plasticity can be defined as behavioral loss or even development of disease symptoms resulting from aberrant plasticity changes in the human brain.
Ahmed, Ananth, Aron, Aron, Baldessarini, Breakefield, Brooks, Byl, Calabresi, Calabresi, Carta, Casey, Casey, Castrén, Cenci, Cenci, Cerasa, Cerasa, Cerasa, Cerasa, Cerasa, Clarke, Crow, Crow, de la Fuente-Fernandez, de la Fuente-Fernandez, Fahn, Ganos, Gottwald, Heckers, Jankovic, Jellinger, Jenner, Kishore, Kishore, Koch, Koch, Koch, Li, Marsden, McEwen, Morgante, Nambu, Obeso, Pakkenberg, Peralta, Picconi, Quartarone, Rascol, Rylander, Salgado-Pineda, Sawada, Sgambato-Faure, Sigwald, Spencer, Teo, Vernon, Vernon, Zesiewicz   +58 more
core   +2 more sources

Vestibular Dysfunction in Parkinson's Disease: A Systematic Review of Signs and Symptoms

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Despite the growing interest in the link between Parkinson's disease (PD) neuropathology and vestibular system, there is still a lack of consensus about the presence of vestibular dysfunctions in PD. Objective This review aims to identify vestibular signs and symptoms reported in PD patients and to summarize and critically appraise ...
Francisco Rosado‐Martins, Beatriz Santos, Cláudia M. Costa, Tiago Eça, Raquel Bouça‐Machado, Joaquim J. Ferreira   +5 more
wiley   +1 more source