Results 71 to 80 of about 1,313,066 (193)

Further focus on the study of freezing of gait

Chinese Journal of Contemporary Neurology and Neurosurgery, 2017
DOI: 10.3969/j.issn.1672-6731.2017.02 ...
Xian-wen CHEN
doaj  

Tracking Genetic Parkinson's Disease with Molecular Imaging: A Systematic Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is a worldwide, complex neurodegenerative disorder influenced by both genetic and environmental factors. Around 15–20% of PD cases are linked to genetic mutations, providing insights into the disease's pathogenesis.
Chiara Meneghini, Luca Gallo, Arianna Sala, Enza Maria Valente, Micol Avenali, Silvia Paola Caminiti   +5 more
wiley   +1 more source

Deep Brain Stimulation of Caudal Zona Incerta for Parkinson's Disease: One‐Year Follow‐Up and Electric Field Simulations

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective To evaluate the effects of bilateral caudal zona incerta (cZi) deep brain stimulation (DBS) for Parkinson's disease (PD) one year after surgery and to create anatomical improvement maps based on patient‐specific simulation of the electric field.
Rasmus Stenmark Persson, Teresa Nordin, Gun‐Marie Hariz, Karin Wårdell, Lars Forsgren, Marwan Hariz, Patric Blomstedt   +6 more
wiley   +1 more source

The utility of dopamine transporter scans for diagnosing Parkinsonian disorders [PDF]

, 2018
Introduction: Dopamine transporter scans are increasingly being used in the diagnosis of clinically undefined Parkinsonism. Aims: To assess the indications for imaging usage and its impact on future clinical management.
O'Corragain, O. A., O\u27Sullivan, Sean S., O'Sullivan, Sean S., O\u27Corragain, O. A., Bogue, Conor O., Crotty, Grace F., Crotty, J. M.   +6 more
core   +1 more source

Transcranial sonography in parkinsonian disorders: clear window or blurred vision?

, 2017
Parkinson's disease is extremely difficult to diagnose, given that no test provides conclusive evidence for the disease. Many patients in the early stages of the disease have very few symptoms or experience symptoms that overlap with other conditions ...
Bouwmans, Angela E. P.
core   +1 more source

The Intraoperative Microlesion Effect Positively Correlates With the Short‐Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange, Naomi I. Kremer, Teus van Laar, Fiete Lange, T. Elien Steendam‐Oldekamp, D. L. Marinus Oterdoom, Anthony R. Absalom, J. Marc C. van Dijk, Gea Drost   +8 more
wiley   +1 more source

Orthostatic Myoclonus—Clinical and Electrophysiological Features in a Large Retrospective Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Orthostatic myoclonus is characterized by irregular, lower limb myoclonic bursts during stance and is a major cause of postural instability and falls. However, studies are limited, and little is known about its pathophysiology. Objectives We sought to define the clinical and electrophysiological features of orthostatic myoclonus in ...
Sai A. Nagaratnam, Niroshan Jeyakumar, Gobishan Jeyakumar, Florence Chang, Duncan Wilson, Paloma Becker, Hugo Morales‐Briceno, Neil Mahant, Victor S.C. Fung   +8 more
wiley   +1 more source

Suppression and treatment of Haloperidol induced extra-pyramidal side effects and anxiety syndrome by the coadministeration of red rice bran oil in rats

International Journal of Endorsing Health Science Research, 2014
Antipsychotic medications may reduce or eliminate symptoms of psychosis. They are not a 'cure' for mental illnesses, but can be an effective part of treating mental disorders.
Farah Naz, Erum Shireen
doaj   +1 more source

Efficacy of IncobotulinumtoxinA (BoNT‐A) Injections in Upper Limb Task‐Specific and Position‐Dependent Tremors

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Task‐specific tremors (TST) and position‐dependent tremors (PDT) are rare isolated focal tremors that impair fine motor control with few effective treatment options. Although botulinum neurotoxin (BoNT) is effective in other tremor syndromes, its evidence in these tremor subtypes remains limited.
Elizabeth K. Boyd, Shangge Jiang, Runjie Bill Shi, Philippe Rizek   +3 more
wiley   +1 more source

Machine Learning Prediction of Hoehn and Yahr Scores at 5‐Years Post‐123I‐Ioflupane SPECT Imaging in a Real‐World Parkinson's Disease Dataset

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) progression is highly heterogeneous, complicating clinical management and prognostication. While machine learning models have been developed using research datasets such as Parkinson's Precision Medicine Initiative (PPMI) and Parkinson's Disease Biomarkers Program (PDBP), their clinical translatability is ...
Xuehua Ye, Mette Niemann Johansen, Balazs Laczi, Mads Peter Horndrup, Michael Zaucha Sørensen, Rasmus Vestergård Madsen, Jan Wolber, Markus Lonsdale, Annemette Lokkegaard, Renee Miller   +9 more
wiley   +1 more source