Results 31 to 40 of about 65,159 (298)

Serious Illness Conversation in the Care of Atypical Parkinsonian Disorders: A Practical Guide for Neurology Clinicians [PDF]

open access: hybridMovement Disorders Clinical Practice, EarlyView.
Abstract Background Compared to Parkinson's disease, atypical parkinsonian disorders (APD) are characterized by a more rapidly progressive course, often leading to profound disability. Effective communication between clinicians, patients, and care partners is essential to support patient‐centered care and shared decision‐making.
Michiko Kimura Bruno   +6 more
openalex   +2 more sources

Atypical parkinsonism: An Update. [PDF]

open access: yes, 2013
Purpose of review: This update discusses novel aspects on genetics, diagnosis, and treatments of atypical parkinsonism published over the past 2 years. Recent findings: A genome-wide association study identified new genetic risk factors for progressive ...
Hoeglinger, GU, Stamelou, M
core   +1 more source

Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models

open access: yesJournal of Tissue Engineering, 2021
Mesenchymal stem cells (MSCs) are a potential source of cell-based disease-modifying therapy in Parkinsonian disorders. A promising approach to develop in vitro culture methods that mimic natural MSC niche is cell priming.
Ha Na Kim   +4 more
doaj   +1 more source

Focused ultrasound and deep brain stimulation for Parkinsonism – Review of literature to investigate tradeoff between safety and efficacy

open access: yesSaudi Journal for Health Sciences, 2022
Parkinsonism is a movement disorder, mostly caused by the neurodegenerative Parkinson's disease (PD), the second most common movement disorder. Its symptoms include rigidity, slow movement, tremor, and disruption of balance.
Uthman Alshenqiti   +4 more
doaj   +1 more source

Impaired perception of biological motion in Parkinson’s disease [PDF]

open access: yes, 2016
OBJECTIVE: We examined biological motion perception in Parkinson’s disease (PD). Biological motion perception is related to one’s own motor function and depends on the integrity of brain areas affected in PD, including posterior superior temporal sulcus.
Cronin-Golomb, Alice   +3 more
core   +1 more source

Use of apomorphine in Parkinsonian patients with neuropsychiatric complications to oral treatment [PDF]

open access: yes, 1997
Neuropsychiatric side effects often complicate anti-Parkinsonian therapy and pose a significant problem in the optimal management of idiopathic Parkinson's disease.
Abbott, R.J.   +6 more
core   +2 more sources

Potential mechanisms for imperfect synchronization in parkinsonian basal ganglia [PDF]

open access: yes, 2012
Neural activity in the brain of parkinsonian patients is characterized by the intermittently synchronized oscillatory dynamics. This imperfect synchronization, observed in the beta frequency band, is believed to be related to the hypokinetic motor ...
Park, Choongseok, Rubchinsky, Leonid
core   +6 more sources

Comparison of 6-[18F]FDOPA PET with Nigrosome 1 detection in patients with parkinsonism

open access: yesEJNMMI Research, 2021
Background The functional 6-[18F]FDOPA positron emission tomography (PET) can be a helpful tool in differentiating parkinsonism with dopaminergic deficiency from clinically similar differential diagnoses.
Enrico Michler   +5 more
doaj   +1 more source

Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. [PDF]

open access: yes, 2016
BackgroundClinical diagnosis of parkinsonian syndromes like Parkinson's disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Boman, Andrea   +8 more
core   +1 more source

Diagnostic Evaluation of 99mTc-TRODAT-1 SPECT in Parkinsonism [PDF]

open access: yesJournal of Research in Clinical Medicine, 2021
Background Parkinsonism as a group of movement disorders, exhibit similar clinical presentation. Therefore, clinically differentiating these diseases is difficult. We investigated the diagnostic value of 99m Tc-TRODAT-1 SPECT in this setting.
Zahra Babaei Aghdam   +5 more
doaj   +1 more source

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